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NCT07548567Recruiting

A Long Axis Approach to the Femoral Artery Block (FAB) for Managing Tourniquet Pain and Hypertension in Below-the-Knee Fracture Surgery

Turning the Probe, Changing the View: A Novel Long Axis Approach to the Femoral Artery Block (FAB) for Managing Tourniquet Pain and Hypertension in Below-the-Knee Fracture Surgery: A Prospective, Randomized, Double-Blind Controlled Trial

Source: ClinicalTrials.gov · Last updated 6 Jul 2026

Brief summary (registry, in English)

This is a prospective, randomized, double-blind controlled trial evaluating an ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a control group. The study will include adult patients (ASA I-III) undergoing below-the-knee fracture surgery with tourniquet application. All patients will receive standardized anesthesia including sciatic nerve block and total intravenous anesthesia. Participants will be randomized into three groups: short-axis FAB, long-axis FAB, or control (saline injection). The primary aim is to assess the effectiveness of the long-axis FAB in reducing tourniquet-induced hypertension. Secondary outcomes include hemodynamic stability, analgesic requirements, pain scores, block characteristics, and procedural performance metrics.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
84 (estimated)
First submitted
16 Apr 2026
Start date
3 Jun 2026
Primary completion date
31 Oct 2027
Lead sponsor
National and Kapodistrian University of Athens
NCT number
NCT07548567

What you commit to

  • Study type: Interventional
  • Planned participants: 84
  • From 3 Jun 2026 to the primary completion date, 31 Oct 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Chronic pain therapy

Other illness

  • Known allergy to study drugs
  • Systemic neurological disease affecting peripheral nerves
  • Uncontrolled hypertension

Other

  • Refusal to participate
  • Local inflammation at block site
  • Morbid obesity (BMI \>40)
  • Communication inability
  • Diabetic neuropathy

Who the study is looking for

  • Age \>18 years
  • Physical status ASA I-III
  • Fluent in Greek or English
  • Scheduled surgery: below-knee fractures
  • Tourniquet duration ≥45 minutes

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University General Hospital Attikon
Coordinator of this site? Confirm its status
AthensGreeceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.