NCT07548801Enrolling by invitation
Cerebellar Transcranial Direct Current Stimulation in Parkinson's Disease
Can Cerebellar Transcranial Direct Current Stimulation be Regarded as a Rational Therapeutic Option for Treating Parkinson's Disease ?
Source: ClinicalTrials.gov · Last updated 23 Apr 2026
Brief summary (registry, in English)
Background \& Rationale: Treatment options for Parkinson's Disease (PD) often face challenges due to the variety of clinical subtypes, differing individual responses, and disease progression. Given its portability, affordability, safety, and ease of use, cerebellar transcranial direct current stimulation (ctDCS) presents as a promising option for home-based treatment with medical telemonitoring in the near future. Study Procedures: Participants are invited to complete questionnaires regarding quality of life, anxiety and depression, and symptoms related to their PD. On the first day, they will be assessed using the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part III for motor impairment and the Cerebellar Cognitive Affective Syndrome scale (CCAS) for cognitive impairment. Participants will then undergo an additional 8 days of at-home cTDCS stimulation. On the 10th day, they will be reassessed using the MDS-UPDRS III and CCAS. One month later, they will complete again the questionnaires regarding quality of life, anxiety, depression, and symptoms related to their PD. Objective: Consequently, the primary goal is to investigate the effectiveness of ctDCS in addressing both motor and non-motor symptoms of PD
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 25 (estimated)
- First submitted
- 1 Apr 2026
- Start date
- 24 Sept 2025
- Primary completion date
- 30 Nov 2026
- Lead sponsor
- Université Libre de Bruxelles
- Diseases
- Parkinson disease
- NCT number
- NCT07548801
What you commit to
- Study type: Interventional
- Planned participants: 25
- From 24 Sept 2025 to the primary completion date, 30 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of an implanted electronic device (e.g., pacemaker, cochlear implants, deep brain stimulator)
Other illness
- History of epileptic seizures
- Active or past neurological condition affecting upper limb control (e.g., stroke, degenerative disease, tumor, traumatic sequelae), or any neuromuscular (e.g., upper limb polyneuropathy, myopathy) or orthopedic condition impairing upper limb motor control
Age
- Patients ≤ 18 years of age
Other
- Pregnant women
- Presence of intracranial metallic hardware (e.g., vascular clips, orthopedic material)
- Subject unable to understand or perform the required motor tasks
- Psychotropic polypharmacy (regular use of neuroleptics, anti-epileptics, benzodiazepines, etc.)
Who the study is looking for
- Patients with mild to moderate PD MDS-UPDRS part 1III or between 1 and 3 on Hoehn and Yahr score
- Patients \> 18 years of agE
- Patients who have signed written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hôpital Erasme Coordinator of this site? Confirm its status | Brussels | Belgium | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.