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NCT07548879Not yet recruiting

Quantitative Analysis of Cardiac Muscle Perfusion

Source: ClinicalTrials.gov · Last updated 23 Apr 2026

Brief summary (registry, in English)

Full quantitative perfusion of the myocardial wall using MRI is a difficult method for several reasons. First the perfusion algorithm is mostly only relatively available, usually available algorithms /e.g. ISP/ shows not precise results according to our measurements, secondly based on signal physics and nature of MRI scans is not easy to get absolute numbers and specific new algorithms must be developed and tested. Such a tool is not only needed for some special cohort of patients, like 3-vessel disease, coronary artery disease or diffuse coronary artery involvement in coronary vasculopathy in patients after heart transplantation. Fully quantitative perfusion analysis is highly needed for nearly all cardiac patients to better characterise the health and status of the myocardium.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
35 (estimated)
First submitted
16 Apr 2026
Start date
1 Jun 2026
Primary completion date
30 Dec 2029
Lead sponsor
St. Anne's University Hospital Brno, Czech Republic
NCT number
NCT07548879

What you commit to

  • Study type: Interventional
  • Planned participants: 35
  • From 1 Jun 2026 to the primary completion date, 30 Dec 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Presence of relative or absolute contraindications to stress testing, including acute coronary syndrome, life-threatening arrhythmias, severe chronic obstructive pulmonary disease (COPD), or second- or third-degree atrioventricular (AV) block.
  • Contraindications to MRI, such as severe claustrophobia, presence of ferromagnetic material or implants, or severe renal impairment.

Who the study is looking for

  • Signed informed consent
  • Patients indicated for a non-invasive test for ischemic heart disease/chronic coronary syndrome
  • Patients with intermittent chest pain and low to moderate probability of chronic coronary syndrome

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
St. Anne's University Hospital Brno
Coordinator of this site? Confirm its status
BrnoCzechiaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.