NCT07549269Completed
Comparison of Nab-Paclitaxel Versus Paclitaxel in Neoadjuvant Immunochemotherapy Therapy for Esophageal Squamous Cell Carcinoma: A Retrospective IPTW-Adjusted Analysis
Source: ClinicalTrials.gov · Last updated 24 Aug 2026
Brief summary (registry, in English)
Taxane-based agents are widely used in the treatment of esophageal squamous cell carcinoma (ESCC). Among these, nab-paclitaxel (albumin-bound paclitaxel) and paclitaxel are the most commonly used. However, there is currently no definitive evidence comparing the efficacy of these two agents in the context of neoadjuvant therapy for ESCC.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 387 (actual)
- First submitted
- 9 Apr 2026
- Start date
- 1 Apr 2026
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- Sichuan University
- NCT number
- NCT07549269
What you commit to
- Study type: Observational
- Participants enrolled: 387
- From 1 Apr 2026 to the primary completion date, 1 Jul 2026
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Receipt of other neoadjuvant treatments, including chemotherapy, chemoradiotherapy, or chemoradiotherapy combined with immunotherapy.
- Incomplete medical records.
Other illness
- Presence of any untreated malignancy within the past five years, except fully treated cervical carcinoma in situ or basal cell carcinoma/squamous cell skin cancer.
Other
- Refusal to participate in follow-up.
Who the study is looking for
- Histologically confirmed diagnosis of esophageal squamous cell carcinoma (ESCC).
- Patients with resectable or potentially resectable disease based on baseline clinical assessment.
Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| West China Hospital Coordinator of this site? Confirm its status | Chengdu | China | Unknown status |
| Mianzhu People's Hospital (West China Mianzhu Hospital, Sichuan University) Coordinator of this site? Confirm its status | Mianzhu | China | Unknown status |
| Suining Central Hospital Coordinator of this site? Confirm its status | Suining | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.