NCT07549425Active, not recruiting
Construction and Validation of an Intelligent Ultrasound Diagnostic System for the Spectrum of Neuroblastoma in Children
Construction and Validation of an Intelligent Ultrasound Diagnostic System for the Spectrum of Neuroblastoma in Children: A Multicenter Study
Source: ClinicalTrials.gov · Last updated 24 Apr 2026
Brief summary (registry, in English)
The goal of this observational study is to build an intelligent ultrasound diagnostic system that integrates pathological typing, risk stratification and prognosis assessment. The main question it aims to answer is: 1. Can the prediction model of neuroblastoma tumors (NTs) in children based on ultrasound images distinguish each pathological subtype? 2. Can the multimodal fusion model established based on clinical and pathological features identify high-risk patients, predict bone marrow metastasis, and estimate the therapeutic effect? 3. Can this ultrasound diagnostic system achieve a systematic and intelligent assessment of NTs patients to assist in clinical risk stratification and individualized treatment decisions?
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 1 Apr 2026
- Start date
- 1 Jan 2026
- Primary completion date
- 30 Apr 2026
- Lead sponsor
- The Children's Hospital of Zhejiang University School of Medicine
- Diseases
- Neuroblastoma, Childhood cancers
- NCT number
- NCT07549425
What you commit to
- Study type: Observational
- Planned participants: 300
- From 1 Jan 2026 to the primary completion date, 30 Apr 2026
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- The patient has previously undergone surgical resection treatment in another hospital, but the tumor recurred or remained after the operation.
Other
- Poor quality of ultrasound images: There are artifacts that seriously affect the identification of tumor contours or feature extraction, image blurring, or incomplete display of the lesion.
- Severe data deficiency: Key clinical pathological data or imaging data are missing, making it impossible to extract and analyze the required information.
Who the study is looking for
- The diagnosis of NTs was confirmed by surgical resection or biopsy with histopathological examination, and the type was classified as NB, GNB or GN according to the INPC standard.
- Age ≤ 18 years old, with no gender restrictions.
- There are complete abdominal (or primary site) ultrasound images archived, in original DICOM or JPG format, with image quality meeting the analysis requirements.
- Complete clinical and pathological data relevant to the research purpose are available.
Age in the registry: - to 18 years · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Zhejiang Cancer Hospital Coordinator of this site? Confirm its status | Hangzhou | China | Unknown status |
| The Children's Hospital of Zhejiang University School of Medicine Coordinator of this site? Confirm its status | Hangzhou | China | Unknown status |
| Anhui Provincial Children's Hospital Coordinator of this site? Confirm its status | Hefei | China | Unknown status |
| Kunming Children's Hospital Coordinator of this site? Confirm its status | Kunming | China | Unknown status |
| The Children's Hospital Affiliated to Soochow University Coordinator of this site? Confirm its status | Suzhou | China | Unknown status |
| Wenling Institute of Medical Big Data and Artificial Intelligence Coordinator of this site? Confirm its status | Wenling | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.