NCT07550257Not yet recruiting
Prospective Registry of Acute Ischemic Stroke in Children Under 18 Years Old in China
Prospective Registry of Acute Ischemic Stroke in Children Under 18 Years Old in China (KIDS-AIS-REGISTRY)
Source: ClinicalTrials.gov · Last updated 24 Apr 2026
Brief summary (registry, in English)
This observational study aims to investigate the real-world effectiveness and safety of different treatment strategies for acute ischemic stroke (AIS) in Chinese children under 18 years of age. Its primary research question is: In real-world clinical practice, does endovascular therapy (e.g., stent retriever thrombectomy, aspiration thrombectomy) improve 90-day functional outcomes in pediatric AIS patients with acute anterior or posterior circulation large vessel occlusion? Children under 18 years of age receiving routine AIS diagnosis and treatment at approximately 25-35 study centers across China will undergo neurological function assessments, imaging examinations, and evaluations of growth, development, and psychosocial status at baseline, 24 hours post-procedure, 7 days post-procedure or at hospital discharge, and at 90 days and 6 months post-onset. Adverse events will also be documented.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 19 Apr 2026
- Start date
- 1 Jun 2026
- Primary completion date
- 31 May 2029
- Lead sponsor
- Gansu Provincial Maternal and Child Health Care Hospital
- Diseases
- Stroke
- NCT number
- NCT07550257
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 1 Jun 2026 to the primary completion date, 31 May 2029
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concurrent presence of indistinguishable ischemic and hemorrhagic stroke
Other illness
- Lack of imaging examination or stroke diagnosed without imaging
- History of hypoxic-ischemic encephalopathy
- Ischemic stroke caused by cerebral venous system
Who the study is looking for
- Age \>28 days and \<18 years;
- Presence of stroke-related symptoms (hemiparesis, facial palsy, aphasia, altered level of consciousness, seizure, headache) or atypical symptoms (sudden lethargy or irritability, crying, feeding difficulties, incontinence, sensory loss, ataxia, vertigo, nausea and/or vomiting, neck pain, fever);
- First-ever stroke and onset within ≤7 days prior to admission;
- Acute ischemic stroke confirmed by computed tomography (CT) or magnetic resonance imaging (MRI);
- Legal guardian provides signed informed consent;
- For children aged ≥8 years to \<18 years who are conscious and without comprehension impairment, assent obtained from the child;
Age in the registry: 28 days to 18 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.