NCT07553871Not yet recruiting
Comparative Study on the Medium- and Long-term Benefits of Prosthesis Selection in Total Knee Arthroplasty
Source: ClinicalTrials.gov · Last updated 28 Apr 2026
Brief summary (registry, in English)
This retrospective real-world study aims to compare the medium- and long-term clinical outcomes, safety, and economic benefits of different knee prosthesis brands used in primary unilateral total knee arthroplasty (TKA) at our hospital. The study will include adult patients who underwent first-time unilateral TKA between January 1, 2022 and December 31, 2025. Outcomes such as postoperative knee function, complications, length of hospital stay, quality of life, and medical costs will be evaluated. The results are expected to provide evidence to support prosthesis selection and optimize healthcare resource allocation.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 3500 (estimated)
- First submitted
- 10 Apr 2026
- Start date
- 31 May 2026
- Primary completion date
- Dec 2026
- Lead sponsor
- Second Affiliated Hospital of Wenzhou Medical University
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT07553871
What you commit to
- Study type: Observational
- Planned participants: 3500
- From 31 May 2026 to the primary completion date, Dec 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Revision knee arthroplasty, simultaneous bilateral arthroplasty, or concomitant arthroplasty of other joints.
Other illness
- Arthroplasty performed for non-degenerative conditions such as tumour or acute trauma.
Other
- Perioperative death or loss to follow-up.
- Severely incomplete clinical data that preclude valid analysis.
Who the study is looking for
- Age \>= 18 years.
- Diagnosis of end-stage knee osteoarthritis, rheumatoid arthritis, or other conditions meeting the indication for TKA.
- First-time unilateral knee arthroplasty.
- Complete medical records, including perioperative records, prosthesis model records, detailed cost information, and regular postoperative follow-up records.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.