NCT07555379Not yet recruiting
Bilateral Anodal Cerebellar tDCS for Multidomain Dysfunctions in Patients With Multiple Sclerosis
Bilateral Anodal Cerebellar tDCS for Multidomain Dysfunctions in Patients With Multiple Sclerosis: A Randomized Controlled Trial Study
Source: ClinicalTrials.gov · Last updated 29 Apr 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if brain stimulation can improve movement and daily function in people with multiple sclerosis (MS). The study will also look at how this treatment affects fatigue, sleep, memory and attention, and quality of life. The main questions this study aims to answer are the following: Does this treatment improve coordination and balance? Does it reduce fatigue and improve sleep and daily life? Does it change brain activity? Researchers will compare active brain stimulation to sham stimulation (a look-alike treatment that does not deliver real stimulation) to see if the treatment works. Participants will: Receive brain stimulation sessions for two weeks Attend assessment sessions before and after treatment Return for a follow-up visit after four weeks Complete tests of movement, fatigue, sleep, and thinking
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 14 Apr 2026
- Start date
- 1 Sept 2026
- Primary completion date
- 1 Mar 2028
- Lead sponsor
- University of Sharjah
- Diseases
- Multiple sclerosis
- NCT number
- NCT07555379
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 1 Sept 2026 to the primary completion date, 1 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Metallic implants in the head or skull incompatible with transcranial magnetic stimulation (TMS)
Other illness
- History of epilepsy or seizures
- Severe cognitive impairment preventing participation in assessments
- Other neurological or psychiatric disorders that may confound study outcomes
- Severe musculoskeletal or orthopedic conditions interfering with motor performance testing
Other
- Multiple sclerosis relapse within the past 3 months
- Presence of implanted electronic devices (e.g., pacemaker, neurostimulator)
- Pregnancy or planned pregnancy during the study period
- Contraindications to non-invasive brain stimulation or TMS
Who the study is looking for
- Confirmed diagnosis of Multiple Sclerosis according to the revised McDonald criteria
- Adult Age \> 18 years
- Expanded Disability Status Scale (EDSS) score between 2.0 and 6.0
- Clinically stable disease status for at least 3 months prior to enrollment
- On stable disease-modifying therapy (DMT) for at least 3 months
- Ability to understand study procedures and provide informed consent
- Ability to ambulate independently or with assistive devices sufficient to complete motor assessments
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Sharjah Coordinator of this site? Confirm its status | Sharjah city | United Arab Emirates | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.