NCT07557680CompletedPhase 3
Dexmedetomidine in Attenuation of Haemodynamic Response to Laryngoscopy in Controlled Hypertensive Patients
Role of Intravenous Dexmedetomidine in Attenuation of Hemodynamic Response to Laryngoscopy in Controlled Hypertensive Patients: A Prospective Randomised Double-Blind Study
Source: ClinicalTrials.gov · Last updated 29 Apr 2026
Brief summary (registry, in English)
This randomized control trial, which was carried out at Sindh Institute of Urology and Transplantation (SIUT), used a non-probability consecutive sampling technique for six months from January 1, 2025, to June 30, 2025.
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 70 (actual)
- First submitted
- 5 Jan 2026
- Start date
- 1 Jan 2025
- Primary completion date
- 30 Jun 2025
- Lead sponsor
- Sindh Institute of Urology and Transplantation
- Diseases
- High blood pressure
- NCT number
- NCT07557680
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 70
- From 1 Jan 2025 to the primary completion date, 30 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- A patient who has not taken an antihypertensive drug early morning on the day of surgery.
Other illness
- Patients with a history of allergy to drugs being used.
- Patients with uncontrolled hypertension (BP \> 140/90 mmHg).
- History of bradycardia (resting heart rate \< 60 bpm).
- Patients on beta blockers if resting heart rate \< 60 bpm.
- History of valvular heart disease, uncontrolled diabetes, liver, or kidney disease.
Other
- Patients with an anticipated difficult intubation.
- Those requiring more than 15 seconds or more than one attempt or use of a bougie during laryngoscopy.
- Pregnancy.
Who the study is looking for
- Ages from 18 to 65 years.
- Patients with a known case of controlled hypertension.
- ASA II
- Elective surgical procedure under general anaesthesia.
- Mallampati grades 1 and 2.
- Patients consenting to participate in this study
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sindh Institute of Urology and Transplantation Coordinator of this site? Confirm its status | Karachi | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.