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NCT07558018Not yet recruiting

Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCA

Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCA: Insights Into Pathophysiology and Diagnosis Using Noninvasive, Innovative Techniques (NOCAWT)

Source: ClinicalTrials.gov · Last updated 5 May 2026

Brief summary (registry, in English)

The primary objective of this project is to validate a multi-modal systemic microvascular phenotyping platform-combining Laser Speckle Contrast Imaging (LSCI) and Sublingual Handheld Videomicroscopy (IDF imaging)-as a non-invasive surrogate for coronary microvascular function in women with ANOCA (Angina with Non-Obstructive Coronary Arteries). We aim to demonstrate that systemic microvascular signatures (microvascular reactivity and density) can predict coronary endotypes with high accuracy, potentially reducing the need for invasive diagnostics.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
60 (estimated)
First submitted
22 Apr 2026
Start date
1 Aug 2026
Primary completion date
31 Dec 2029
Lead sponsor
National Institute of Cardiology, Laranjeiras, Brazil
NCT number
NCT07558018

What you commit to

  • Study type: Observational
  • Planned participants: 60
  • From 1 Aug 2026 to the primary completion date, 31 Dec 2029
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Malignant neoplasms
  • Autoimmune diseases
  • Acute systemic diseases
  • Iodine allergy

Other

  • Pregnancy or lactation
  • CAD on invasive coronary angiography or coronary computed tomography angiography (CCTA)

Who the study is looking for

  • Age 18-65 years
  • Anginal chest pain

Age in the registry: 18 years to 65 years · Sex: Female

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.