NCT07560540Recruiting
Nutritional Intervention Implication in Enhanced Recovery After Surgery for Whipple Procedure
Implication of Nutritional Intervention in Enhanced Recovery After Surgery for Whipple Procedure/Pylorus Preserving Pancreatoduodenectomy
Source: ClinicalTrials.gov · Last updated 1 May 2026
Brief summary (registry, in English)
The objective of this research is to assess the impact of personalized nutritional intervention on postoperative complications and length of stay in Whipple's patients via assessing the parameters related to body composition, nutritional status, weight maintenance, biochemical profile (LFTs, RFTs, CBC, CRP, serum electrolytes, coagulation profile and HbA1c) and muscle preservation postoperatively. Moreover, enhanced recovery after surgery (ERAS) guidelines in Whipple's patients will also be monitored. Exactly 20 patients undergoing Whipple's Procedure/PPPD in 1 year will be recruited for the study. Medical nutrition therapy will include energy intake of 25- 30 Kcal/kg body weight and protein 1.2-1.5g/kg body weight. Enteral nutrition and parenteral nutrition will be given accordingly. After discharge, patients receiving chemotherapy and patients not receiving chemotherapy will be nutritionally intervened accordingly. Follow-ups will be done in the 2nd week, 3rd month and 6th month after surgery. Data will be analyzed using SPSS version 27. To assess the significant difference among study groups t-test, repeated measure analysis of variance (ANOVA) and regression model will be applied. The level of significance will be kept at 5%. t-test for treatment groups.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 31 Mar 2026
- Start date
- Dec 2025
- Primary completion date
- Dec 2026
- Lead sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
- Diseases
- Pancreatic cancer
- NCT number
- NCT07560540
What you commit to
- Study type: Interventional
- Planned participants: 20
- From Dec 2025 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients undergoing Whipple's procedure for reasons other than malignancy
Age
- Age below 18
Other
- Patients undergoing emergency procedures
- Patients with significant preoperative complications prohibiting oral intake
Who the study is looking for
- Malignancy of;
- Distal common bile duct
- Pancreatic head
- Periampullary
- Duodenal
- Patients scheduled for elective Whipple's procedure (laparoscopic and open)
- Age 18 and above
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shalamar Hospital Coordinator of this site? Confirm its status | Lahore | Pakistan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.