NCT07566065Not yet recruiting
Covered vs Bare Metal Stents for Atherosclerotic Renal Artery Stenosis
Endovascular Treatment of Atherosclerotic Renal Artery Stenosis: A Prospective Randomized Controlled Study Comparing Covered Stents and Bare Metal Stents
Source: ClinicalTrials.gov · Last updated 4 May 2026
Brief summary (registry, in English)
Atherosclerotic renal artery stenosis is the most common cause of secondary hypertension , increasing the risk of cardiovascular and kidney-related complications. Some small-scale studies have suggested that covered stents are effective and safe, but high-quality evidence from large-scale studies in atherosclerotic renal artery stenosis remains limited. This study aims to evaluate whether covered stents are more effective than bare metal stents in patients with atherosclerotic renal artery stenosis. Eligible participants will be randomly assigned to receive either a covered stent or a bare metal stent. Patients will be followed for 12 months to assess Changes in eGFR, 24-hour systolic blood pressure, and 24-hour diastolic blood pressure from baseline to 12 months were compared among the groups. The results of this study may help improve treatment strategies and guide the selection of stent type for patients with this condition.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 27 Apr 2026
- Start date
- 30 Apr 2026
- Primary completion date
- 30 Apr 2027
- Lead sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
- Diseases
- High blood pressure
- NCT number
- NCT07566065
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 30 Apr 2026 to the primary completion date, 30 Apr 2027
- 15 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- 1\) Unstable clinical condition rendering the patient intolerant to revascularisation therapy; 2) Urinary protein ≥2+; 3) Contrast medium allergy; 4) Renal artery anatomy unsuitable for revascularisation therapy; 5) Reference vessel diameter \<3.5mm or \>8mm. 6)Patients with non-atherosclerotic renal artery stenosis (such as fibromuscular dysplasia or Takayasu arteritis); 7)Reference vessel diameter \< 3.5 mm or \> 8 mm
Who the study is looking for
- 1\) Renal artery diameter stenosis ≥60%; 2) Office systolic blood pressure ≥ 160 mmHg and/or office diastolic blood pressure ≥ 100 mmHg on at least two separate days without antihypertensive medication, or office systolic blood pressure ≥ 140 mmHg and/or office diastolic blood pressure ≥ 90 mmHg while on three antihypertensive drugs at conventional doses; 3) Serum creatinine \< 264 μmol/L (3.0 mg/dL); 4) Affected kidney length ≥ 7.0 cm, with residual glomerular filtration rate (GFR) ≥ 10 mL/min;
Age in the registry: 40 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (15)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037 Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
| The Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu Coordinator of this site? Confirm its status | Chengdu | China | Unknown status |
| Department of Cardiovascular Medicine, Cardiovascular Research Center , The First Affiliated Hospital of Chongqing Medical University Coordinator of this site? Confirm its status | Chongqing | China | Unknown status |
| Frist Aiffiliated Hospital of Dalian Medical University Coordinator of this site? Confirm its status | Dalian | China | Unknown status |
| Affilated Zhongshan Hospital of Dalian University Coordinator of this site? Confirm its status | Dalian | China | Unknown status |
| the First Affiliated Hospital of Sun Yat-sen University Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
| The Second Affiliated Hospital of Harbin Medical University, Ha'erbin Coordinator of this site? Confirm its status | Harbin | China | Unknown status |
| The Second Affiliated Hospital of Harbin Medical University Coordinator of this site? Confirm its status | Harbin | China | Unknown status |
| China-Japan Union Hospital of Jilin University, Changchun, Lilin Coordinator of this site? Confirm its status | Jilin City | China | Unknown status |
| Qilu Hospital of Shandong University Coordinator of this site? Confirm its status | Jinan | China | Unknown status |
| Jiangxi Provincial People's Hospital (The First Affiliated Hospital of Nanchang Medical College) Coordinator of this site? Confirm its status | Nanchang | China | Unknown status |
| Nanjing Pukou People's Hospital(Liangjiang Hospital Southeast University) Coordinator of this site? Confirm its status | Nanjing | China | Unknown status |
| Qingdao Hospital University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital) Coordinator of this site? Confirm its status | Qingdao | China | Unknown status |
| Fuwai Central China Cardiovascular Hospital Coordinator of this site? Confirm its status | Zhengzhou | China | Unknown status |
| Zhengzhou Central Hospital Affiliated to Zhengzhou University Coordinator of this site? Confirm its status | Zhengzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.