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NCT07566065Not yet recruiting

Covered vs Bare Metal Stents for Atherosclerotic Renal Artery Stenosis

Endovascular Treatment of Atherosclerotic Renal Artery Stenosis: A Prospective Randomized Controlled Study Comparing Covered Stents and Bare Metal Stents

Source: ClinicalTrials.gov · Last updated 4 May 2026

Brief summary (registry, in English)

Atherosclerotic renal artery stenosis is the most common cause of secondary hypertension , increasing the risk of cardiovascular and kidney-related complications. Some small-scale studies have suggested that covered stents are effective and safe, but high-quality evidence from large-scale studies in atherosclerotic renal artery stenosis remains limited. This study aims to evaluate whether covered stents are more effective than bare metal stents in patients with atherosclerotic renal artery stenosis. Eligible participants will be randomly assigned to receive either a covered stent or a bare metal stent. Patients will be followed for 12 months to assess Changes in eGFR, 24-hour systolic blood pressure, and 24-hour diastolic blood pressure from baseline to 12 months were compared among the groups. The results of this study may help improve treatment strategies and guide the selection of stent type for patients with this condition.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
150 (estimated)
First submitted
27 Apr 2026
Start date
30 Apr 2026
Primary completion date
30 Apr 2027
Lead sponsor
Chinese Academy of Medical Sciences, Fuwai Hospital
NCT number
NCT07566065

What you commit to

  • Study type: Interventional
  • Planned participants: 150
  • From 30 Apr 2026 to the primary completion date, 30 Apr 2027
  • 15 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • 1\) Unstable clinical condition rendering the patient intolerant to revascularisation therapy; 2) Urinary protein ≥2+; 3) Contrast medium allergy; 4) Renal artery anatomy unsuitable for revascularisation therapy; 5) Reference vessel diameter \<3.5mm or \>8mm. 6)Patients with non-atherosclerotic renal artery stenosis (such as fibromuscular dysplasia or Takayasu arteritis); 7)Reference vessel diameter \< 3.5 mm or \> 8 mm

Who the study is looking for

  • 1\) Renal artery diameter stenosis ≥60%; 2) Office systolic blood pressure ≥ 160 mmHg and/or office diastolic blood pressure ≥ 100 mmHg on at least two separate days without antihypertensive medication, or office systolic blood pressure ≥ 140 mmHg and/or office diastolic blood pressure ≥ 90 mmHg while on three antihypertensive drugs at conventional doses; 3) Serum creatinine \< 264 μmol/L (3.0 mg/dL); 4) Affected kidney length ≥ 7.0 cm, with residual glomerular filtration rate (GFR) ≥ 10 mL/min;

Age in the registry: 40 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (15)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037
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BeijingChinaUnknown status
The Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu
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ChengduChinaUnknown status
Department of Cardiovascular Medicine, Cardiovascular Research Center , The First Affiliated Hospital of Chongqing Medical University
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ChongqingChinaUnknown status
Frist Aiffiliated Hospital of Dalian Medical University
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DalianChinaUnknown status
Affilated Zhongshan Hospital of Dalian University
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DalianChinaUnknown status
the First Affiliated Hospital of Sun Yat-sen University
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GuangzhouChinaUnknown status
The Second Affiliated Hospital of Harbin Medical University, Ha'erbin
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HarbinChinaUnknown status
The Second Affiliated Hospital of Harbin Medical University
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HarbinChinaUnknown status
China-Japan Union Hospital of Jilin University, Changchun, Lilin
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Jilin CityChinaUnknown status
Qilu Hospital of Shandong University
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JinanChinaUnknown status
Jiangxi Provincial People's Hospital (The First Affiliated Hospital of Nanchang Medical College)
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NanchangChinaUnknown status
Nanjing Pukou People's Hospital(Liangjiang Hospital Southeast University)
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NanjingChinaUnknown status
Qingdao Hospital University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital)
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QingdaoChinaUnknown status
Fuwai Central China Cardiovascular Hospital
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ZhengzhouChinaUnknown status
Zhengzhou Central Hospital Affiliated to Zhengzhou University
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ZhengzhouChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.