NCT07568938Recruiting
Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA for Bariatric Surgery
Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA TCI ELEVELD Model for Bariatric Surgery
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
The goal of this clinical trial is to compare the effects of Opioid Free Anesthesia (OFA) with and without volatile anesthetics (in this case desflurane) in patients undergoing bariatric surgery. The main question it aims to answer : -Will there be a difference in the perioperative stress between patients receiving OFA with and without desflurane? Participants will undergoing sleeve gastrectomy or gastric by pass, will be administered OFA with and without desflurane and blood tests (cortisole, ACTH,dopamine, PRL, adrenaline, noradrenaline, lactate) will be collected perioperatively to compare stress in the two groups.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 25 Apr 2026
- Start date
- Jan 2024
- Primary completion date
- Feb 2027
- Lead sponsor
- G.Gennimatas General Hospital
- Diseases
- Obesity
- NCT number
- NCT07568938
What you commit to
- Study type: Interventional
- Planned participants: 70
- From Jan 2024 to the primary completion date, Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who have received corticosteroids for durations \>3 weeks at any point in their lifetime
Other illness
- Known allergy or hypersensitiity to any of the medications administered
Other
- Patients declining or withdrawing consent
- Patients unsuitabe with regards to compliance to treatment, according to the researcher's assessment
- Bradycardia, AV block, , postural hypotension
- QTcF\>470msec
- Stop-BANG score \>6
- Intraoperative administration of more than 8mg of prednisolone or equivalent
- Participation in other clinical trial for experimental product administered post operatively
- Diagnosis of depression
Who the study is looking for
- Signed Informed Consent
- ASA II-III
- Morbid obesity confirmed diagnosis and approval for surgical treatment
- Laparoscopic sleeve gastrectomy (LSG) or Gastric By pass (R-Y By pass /SASI/SADI AND one anastomosis by pass )
- Preop respiratrory assessment conducted
- Adequate organ and bone marrow function
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| General Hospital of Athens "G. Gennimatas" Coordinator of this site? Confirm its status | Athens | Greece | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.