NCT07570407Recruiting
Quantification of Peripheral Blood iNKTs After Allogeneic Stem Cell Transplantation
Standardised Quantification of Invariant NKT Cells Using DryTube Technology and Flow Cytometry in Patients Who Have Undergone Allogeneic Haematopoietic Stem Cell Transplantation.
Source: ClinicalTrials.gov · Last updated 13 Aug 2026
Brief summary (registry, in English)
The transplantation of allogeneic haematopoietic stem cells (HSCs) can lead to serious complications after transplantation, such as graft-versus-host disease (GvHD), infections and relapse due to immunosuppression. Invariant NKT cells (iNKT cells) play a pivotal role in modulating the immune response and have been demonstrated to be instrumental in the pathogenesis of GvHD, cytomegalovirus (CMV) infection, and relapse. Their levels are associated with the development of these complications. This multicentre study aims to test the feasibility of standardising iNKT cell monitoring and to investigate the association between iNKT cell levels and post-transplant complications.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 75 (estimated)
- First submitted
- 16 Apr 2026
- Start date
- 1 Aug 2026
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- University Hospital Pilsen
- Diseases
- Acute myeloid leukemia
- NCT number
- NCT07570407
What you commit to
- Study type: Observational
- Planned participants: 75
- From 1 Aug 2026 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior transplant
Other illness
- Uncontrolled Malignancy
Who the study is looking for
- Diagnosis: AML (exlusion of secondary disease)
- Disease status at time of HSCT: complete remission
- Karnofsky performance status: ≥80%
- Source of HSC: PBSC
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Pilsen Coordinator of this site? Confirm its status | Pilsen | Czechia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.