NCT07570771Recruiting
IMPACT OF DIALYSIS DURATION AND DIURESIS ON BLADDER CAPACITY AND COMPLIANCE IN END STAGE RENAL DISEASE PATIENTS AWAITING RENAL TRANSPLANT
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
Patients with end-stage renal disease (ESRD) who are on dialysis for a long time may experience bladder problems as their urine output decreases and normal bladder filling is lacking. As a result, bladder capacity may be reduced and compliance may deteriorate, which can impact the success of kidney transplantation. Our prospective observational study is designed to investigate how dialysis duration and residual urine output (diuresis) influence bladder capacity and compliance in ESRD patients who are waiting for kidney transplantation. The adult patients undergoing regular dialysis will be assessed clinically, and they will also be subjected to laboratory tests, imaging, and urodynamic studies. Through this study, we aim to determine the frequency of bladder malfunction and its correlation with the length of dialysis and the amount of urine excretion. The results might enhance the pre-transplant workup and offer a basis for urological post-transplantation management that could minimize complications.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 87 (estimated)
- First submitted
- 29 Apr 2026
- Start date
- 2 Feb 2026
- Primary completion date
- 28 Feb 2027
- Lead sponsor
- Sindh Institute of Urology and Transplantation
- Diseases
- Chronic kidney disease
- NCT number
- NCT07570771
What you commit to
- Study type: Observational
- Planned participants: 87
- From 2 Feb 2026 to the primary completion date, 28 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with prior urological surgeries
- Patients on medications affecting lower urinary tract function
Other illness
- Patients with diabetes mellitus
- Patients with active urinary tract infection
- Patients with neurological or systemic diseases affecting bladder function
Other
- Patients with neurogenic bladder
- Patients with pre-existing lower urinary tract symptoms before dialysis
Who the study is looking for
- Patients aged 18-65 years diagnosed with end-stage renal disease (ESRD)
- Patients on maintenance dialysis for a duration of 6 to 24 months
- ESRD secondary to non-urological causes
- Patients awaiting renal transplantation
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sindh Institute of Urology and Transplantation (SIUT) Coordinator of this site? Confirm its status | Karachi | Pakistan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.