NCT07573072Completed
Characterization of the Methylation Profile of Stored Human Samples
Characterization of the Methylation Profile of Samples Stored at the Biological Resource Center (CRB) of the Rizzoli Orthopedic Institute (IOR)
Source: ClinicalTrials.gov · Last updated 7 May 2026
Brief summary (registry, in English)
The project, funded by the PNRR under Mission 4 "Education and Research," aims to strengthen the network of Italian biobanks by improving data management in accordance with the FAIR principles (Findable, Accessible, Interoperable, Reusable). The University of Trento has issued a call for proposals to support Italian biobanks in characterizing samples and expanding associated datasets using advanced technologies. The Biological Resource Center at the Rizzoli Orthopedic Institute in Bologna participated in this call for proposals, requesting funding to analyze the DNA methylation profiles of three patient cohorts: those with inflammatory/degenerative diseases, sarcomas, and rare genetic musculoskeletal disorders. This study will contribute to understanding the biological significance of methylation and exploring its diagnostic and therapeutic potential. The initiative aims to generate data useful for personalized medicine and improve the management of the diseases involved.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 90 (actual)
- First submitted
- 24 Apr 2026
- Start date
- 28 Mar 2025
- Primary completion date
- 22 Jul 2025
- Lead sponsor
- Istituto Ortopedico Rizzoli
- Diseases
- Childhood cancers, Sarcoma
- NCT number
- NCT07573072
What you commit to
- Study type: Observational
- Participants enrolled: 90
- From 28 Mar 2025 to the primary completion date, 22 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patients who have refused to consent to the use of their samples or the processing of their data for genetic studies
- Patients who have refused to consent to the transfer of their samples outside the IOR
Who the study is looking for
- Be a patient with a sample stored in one of the biobanks belonging to the CRB IOR
- Have one of the following conditions: a rare skeletal disorder, sarcoma, or inflammatory arthritis.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IRCCS Istituto Ortopedico Rizzzoli Coordinator of this site? Confirm its status | Bologna | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.