NCT07576374Not yet recruiting
Specificities of Atypical Non AutoImmune Diabetes (ANAID) in the French West Indies
Epidemiological, Clinical, Biological and Genetic Specificities of Atypical Non-AutoImmune Diabetes (ANAID) in the French West Indies
Source: ClinicalTrials.gov · Last updated 8 May 2026
Brief summary (registry, in English)
Genetics variants could be involved in atypical non-autoimmune diabetes revealed by ketoacidosis. The objective of this research will be to determine the relationships between the genetic variants already described in known monogenic diabetes or identified as involved in glucose metabolism and its regulation, in insulin signaling pathways or in insulin secretion itself in subjects of African and Indian ancestry with atypical forms of non autoimmune diabetes.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 118 (estimated)
- First submitted
- 4 May 2026
- Start date
- 1 Jun 2026
- Primary completion date
- 30 Sept 2029
- Lead sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
- Diseases
- Type 2 diabetes
- NCT number
- NCT07576374
What you commit to
- Study type: Observational
- Planned participants: 118
- From 1 Jun 2026 to the primary completion date, 30 Sept 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Type 1 diabetes (T1D) Presence of T1D antibodies Secondary diabetes (pancreas diseases, endocrine diseases, drug intake, infection) Other associated autoimmune pathologies Pregnancy Refusal to participate
Who the study is looking for
- Phenotypic criteria :
- Subjects from Indian or African Ancestry self-declared
- Age criteria at diagnosis:
- Early onset of diabetes: patient aged between 18 and 47 years at the time of diagnosis of diabetes Clinical criteria: at least 2 criteria Labeled type 2 diabetic
- Patient hospitalized for:
- Ketoacid decompensation Significant weight loss (more than 10% in less than 6 months) without obvious etiology Lipodystrophic / lipoatrophic appearance Presence of an associated myopathy or deafness Presence of early inaugural nephropathy or within 3 years after diagnosis Presence of early inaugural heart disease or within 3 years after diagnosis Poor response to non-insulin treatments despite good adherence
- Biological criteria:
- Absent T1D autoantibodies:
- Anti-islet antibodies (ICA) Anti-IA2 antibodies Anti-insulin antibodies Anti-ZnT8 antibodies Anti-GAD antibodies
- Other criteria:
- Informed consent signed by the patient
Age in the registry: 18 years to 47 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier Universitaire de la Guadeloupe Coordinator of this site? Confirm its status | Les Abymes | Guadeloupe | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.