NCT07576790Not yet recruiting
Evaluation of Balloon Guide Catheter as Proximal Protection During Carotid Artery Stenting (EMBO-PROTECT)
Evaluation of Balloon Guide Catheter as Proximal Protection During Carotid Artery Stenting: A Randomized Study (EMBO-PROTECT)
Source: ClinicalTrials.gov · Last updated 8 May 2026
Brief summary (registry, in English)
Carotid angioplasty and stenting (CAS) is an effective treatment for carotid artery stenosis but carries a risk of cerebral embolization. This prospective randomized study evaluates the safety and efficacy of proximal embolic protection using a balloon guide catheter during CAS by comparing the incidence of diffusion-weighted MRI-detected microembolisms and symptomatic thromboembolic events between protected and unprotected procedures.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 126 (estimated)
- First submitted
- 26 Mar 2026
- Start date
- 1 Jul 2026
- Primary completion date
- 1 Jul 2027
- Lead sponsor
- Instituto de Investigación Marqués de Valdecilla
- Diseases
- Stroke
- NCT number
- NCT07576790
What you commit to
- Study type: Interventional
- Planned participants: 126
- From 1 Jul 2026 to the primary completion date, 1 Jul 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous disabling stroke or symptomatic intracranial hemorrhage
- Contraindications to anticoagulant or antiplatelet therapy
- Lack of prior dual antiplatelet therapy
Other illness
- Severe renal failure
- Acute coronary syndrome within 30 days
- Contrast media allergy
Other
- Vascular anatomy unsuitable for balloon guide catheter placement
- Evidence of carotid thrombus
- Severe common carotid artery lesion
- Chronic atrial fibrillation on oral anticoagulation
- Contraindications to MRI
Who the study is looking for
- Age ≥ 18 years
- Symptomatic or asymptomatic carotid artery stenosis
- Candidate for carotid artery stenting
- Written informed consent provided
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.