NCT07578220Recruiting
A Randomized Trial of Ultrasound-Guided Acupotomy for Ankylosing Spondylitis
Ultrasound-Guided Acupotomy for Ankylosing Spondylitis: A Protocol for a Participant- and Assessor-Blinded, Sham-Controlled Randomized Trial
Source: ClinicalTrials.gov · Last updated 15 Oct 2026
Brief summary (registry, in English)
This study employs a randomized controlled trial methodology to systematically evaluate the efficacy and safety of a modified acupotomy technique in the treatment of ankylosing spondylitis. Through ultrasound-guided localization, the operative sites are assessed to clarify the improvement effect of the modified acupotomy on disease activity in AS patients. The aim is to enhance the clinical outcomes of AS, provide evidence-based medical support for acupotomy treatment of AS, and improve the diagnosis and treatment standards for the condition.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 5 May 2026
- Start date
- 2 Dec 2025
- Primary completion date
- 30 Apr 2028
- Lead sponsor
- China-Japan Friendship Hospital
- Diseases
- Ankylosing spondylitis
- NCT number
- NCT07578220
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 2 Dec 2025 to the primary completion date, 30 Apr 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Complete spinal ankylosis, severe spinal deformity, previous spinal surgery, or spinal trauma affecting the target treatment area;
- Use of biologic agents, targeted synthetic disease-modifying antirheumatic drugs (tsDMARDs), conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), systemic corticosteroids, or other immunomodulatory therapies within the previous month;
- Previous acupotomy treatment at the target anatomical site within the previous 3 months;
Other illness
- Presence of other autoimmune or inflammatory rheumatic diseases that may affect outcome assessment, including psoriatic arthritis, reactive arthritis, or inflammatory bowel disease-associated spondyloarthritis;
- Severe cardiovascular or cerebrovascular disease, severe hepatic or renal dysfunction, malignancy, coagulation disorders, or other conditions considered unsuitable for the intervention;
- Cognitive impairment or communication difficulties that may affect outcome assessment;
- Known metal allergy or severe fear of acupotomy procedures.
Other
- Pregnancy or breastfeeding;
Who the study is looking for
- Meeting the 1984 revised New York criteria or the 2009 Assessment of SpondyloArthritis International Society (ASAS) classification criteria for axial spondyloarthritis.
- Aged 18-75 years.
- Bath Ankylosing Spondylitis Disease Activity Index (BASDAl) score ≥4.
- Provision of written informed consent.
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Second Affiliated Hospital of Henan University of Chinese Medicine Coordinator of this site? Confirm its status | Henan | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.