NCT07580612Recruiting
AID-FOG: Artificial Intelligence-Driven Freezing of Gait Detection in the Home
Artificial Intelligence-Driven Freezing Of Gait Detection in the Home: Investigating How Free-living Activities Affect the Algorithm
Source: ClinicalTrials.gov · Last updated 12 May 2026
Brief summary (registry, in English)
Freezing of gait (FOG) is a debilitating symptom of Parkinson's disease increases the risk of falling. Despite being a common symptom, it is still difficult to evaluate freezing of gait quickly and accurately. Currently, the gold-standard method to determine the severity of FOG is a manual analysis of video footage by an experienced assessor, collected during standardized FOG-provoking walking tests. Because this is a very time-intensive process, where different assessors sometimes obtain different results, our team at KU Leuven have developed an artificial-intelligent (AI) algorithm trained to identify FOG episodes based on wearable inertial measurement unit (IMU) sensor data. The AI algorithm has already undergone initial validation during laboratory testing, yielding promising results. The aim of this study is to investigate whether the AI algorithm can accurately detect FOG episodes in a less controlled environment, namely the home environment. In a second phase, the investigators will also use the collected data to improve the AI algorithm for automated FOG detection in the home. Finally, the investigators want to explore whether the AI algorithm can detect FOG in real-time.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 126 (estimated)
- First submitted
- 2 Apr 2026
- Start date
- 22 Sept 2025
- Primary completion date
- Jun 2027
- Lead sponsor
- KU Leuven
- Diseases
- Parkinson disease
- NCT number
- NCT07580612
What you commit to
- Study type: Observational
- Planned participants: 126
- From 22 Sept 2025 to the primary completion date, Jun 2027
- 3 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Occurrence of any of the following within 3 months prior to informed consent: myocardial infarction, hospitalization for unstable angina, stroke, coronary artery bypass graft (CABG), percutaneous coronary intervention (PCI), implantation of a cardiac resynchronization therapy device (CRTD), active treatment for cancer or other malignant disease, uncontrolled congestive heart disease (NYHA class \>3), acute psychosis or major psychiatric disorders or continued substance abuse, other neurological (than PD) or orthopaedic impairment that significantly impacts on gait;
Other
- Participant self-reports daily falls;
- Participation in another interventional study, with or without an investigational medicinal product (IMP) or device (IMD)
Who the study is looking for
- For all participants
- Voluntary written informed consent of the participant has been obtained prior to any study-related procedures, except the non-recorded pre-screening questions;
- At least 18 years of age at the time of signing the Informed Consent Form (ICF);
- Person is cognitively able to follow and understand instructions and provide voluntary written informed consent;
- Person is able to walk for short distances (± 10 meters) independently, with- or without use of a walking aid;
- Person does not live in a temporary or permanent care facility.
- For participants with PD:
- Clinical diagnosis of Parkinson's disease (PD) made by a neurologist according to the Movement Disorders Society guidelines;
- Person self-reports to experience daily FOG (for recruitment of freezers only);
- Person is willing to temporarily delay the morning anti-Parkinsonian medication during the standardized assessment visit.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of rehabilitation sciences Coordinator of this site? Confirm its status | Leuven | Belgium | Recruiting |
| Sports Science and Neurorehabilitation Coordinator of this site? Confirm its status | Hamburg | Germany | Not yet recruiting |
| Center for the study of movement, cognition and mobility Coordinator of this site? Confirm its status | Tel Aviv | Israel | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.