NCT07581964Completed
Effect of Sleep Apnea on Pain After Dental Treatment
Relationship Between Obstructive Sleep Apnea and Postoperative Pain After Endodontic Treatment
Source: ClinicalTrials.gov · Last updated 12 May 2026
Brief summary (registry, in English)
This observational study aims to investigate the effects of sleep quality and systemic health status on pain levels following endodontic treatment in adult patients. The primary goal is to determine how obstructive sleep apnea and common systemic conditions (diabetes and hypertension) influence postoperative dental pain. The key questions it aims to answer are: Does the severity of Obstructive Sleep Apnea (OSA) lead to higher postoperative pain scores after root canal treatment? How does the presence of systemic diseases, such as diabetes and hypertension, affect pain perception compared to healthy individuals and OSA patients? Comparison Groups: Researchers will compare outcomes across three distinct cohorts: OSA Group: Patients diagnosed with moderate-to-severe obstructive sleep apnea via polysomnography. Systemic Disease Group: Patients with diagnosed systemic conditions, specifically diabetes and hypertension. Control Group: Systemically healthy individuals without sleep disorders. Participants will: Undergo a polysomnography (PSG) evaluation to assess their sleep status. Receive routine, standard-of-care endodontic treatment. Record and report their pain intensity using the Visual Analog Scale (VAS) at specific intervals after the procedure.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 78 (actual)
- First submitted
- 6 May 2026
- Start date
- Sept 2025
- Primary completion date
- Mar 2026
- Lead sponsor
- Harran University
- Diseases
- High blood pressure, Type 2 diabetes
- NCT number
- NCT07581964
What you commit to
- Study type: Observational
- Participants enrolled: 78
- From Sept 2025 to the primary completion date, Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Chronic use of analgesics or long-term pain-management medications.
Other illness
- Failure to complete the established study protocol.
Other
- Presence of periapical lesions identified during preoperative radiographic evaluation.
- Pregnancy.
Who the study is looking for
- Patients aged between 18 and 65 years.
- Clinical requirement for endodontic (root canal) treatment.
- Presence of a restorable tooth structure.
- Diagnosis of moderate (AHI 15-30) or severe (AHI \> 30) obstructive sleep apnea (OSA) confirmed by polysomnography, for relevant groups.
- Patients with diagnosed systemic diseases (Diabetes Mellitus and/or Hypertension) or systemically healthy controls according to group allocation.
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Harran University Faculty of Dentristry,Departman of Endodonti Coordinator of this site? Confirm its status | Sanliurfa | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.