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NCT07582601Not yet recruiting

SWedish Intensive Care Biobank

Hereditary Influence on Risk Factors for Severe Illness in a Swedish Intensive Care Biobank

Source: ClinicalTrials.gov · Last updated 13 May 2026

Brief summary (registry, in English)

The goal of this observational study is to understand the genetic and molecular risk factors for developing critical illness in adult intensive care unit (ICU) patients in Sweden. The main questions it aims to answer are: Which genetic variants are associated with increased risk of critical illness from conditions such as infections, sepsis, and organ failure? Can circulating proteins and metabolites mediate the effect of genetic risk factors on the severity of illness? Participants will: Provide blood samples at ICU admission and again 3-6 months after discharge Consent to genetic analysis and data linkage with national health registries Have their ICU treatment and outcomes followed using registry and clinical data This study aims to build a national infrastructure for rapid sample collection and analysis that can also support research in future pandemics.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
25000 (estimated)
First submitted
24 Nov 2025
Start date
1 Jan 2027
Primary completion date
30 Dec 2035
Lead sponsor
Uppsala University
NCT number
NCT07582601

What you commit to

  • Study type: Observational
  • Planned participants: 25000
  • From 1 Jan 2027 to the primary completion date, 30 Dec 2035
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Non adults
  • Not admitted to intensive care

Who the study is looking for

  • Adults admitted to intensive care in Sweden

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.