Fact CheckerSign in

NCT07582653Enrolling by invitation

OCTive: A New Horizon in MS Digital Solution

Measuring Motor Symptoms in Clinical Conditions OR Objective Measures to Monitor the Progression of Motor Symptoms of Clinical Conditions

Source: ClinicalTrials.gov · Last updated 13 May 2026

Brief summary (registry, in English)

Multiple Sclerosis (MS) is a condition that affects the brain and spinal cord, leading to problems with movement, balance, and vision. This project will validate innovative tools developed for monitoring MS progression using advanced movement analysis and retinal imaging technologies. Two computer vision-based applications, Digi Motion and Digi Balance, will measure range of motion, centre of mass, balance, and stability. In parallel, a model will be trained to analyse eye images using Optical Coherence Tomography (OCT)-a non-invasive technique that captures detailed views of retinal structures, including the retinal nerve fibre layer (RNFL), ganglion cell-inner plexiform layer (GC-IPL), and macular thickness, which are key biomarkers of MS-related neuroaxonal loss. These tools will be evaluated in people with MS, comparing results with traditional clinical assessments to determine reliability and validity. By integrating movement and retinal biomarkers, this approach aims to create a comprehensive and personalised method for tracking disease progression.

Status (registry)
Enrolling by invitation
Study type
Observational
Enrollment
10 (estimated)
First submitted
2 Feb 2026
Start date
1 Feb 2026
Primary completion date
31 Mar 2026
Lead sponsor
University of Exeter
NCT number
NCT07582653

What you commit to

  • Study type: Observational
  • Planned participants: 10
  • From 1 Feb 2026 to the primary completion date, 31 Mar 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • allergic to adhesive materials
  • a condition that precludes safe participation in the assessment as indicated by the referring clinician

Other

  • pregnancy
  • insufficient mental capacity to consent

Who the study is looking for

  • condition has been stable over a period of a month
  • can walk at least 10 metres independently with or without their walking aids

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Exeter Engineering Research Centre
Coordinator of this site? Confirm its status
ExeterUnited KingdomUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.