NCT07582718Recruiting
Effects of Whole-Body High-Intensity Interval Training on Fitness in Overweight Adults
Effects of a Whole-body High-intensity Interval Training on Cardiorespiratory Fitness, Musculoskeletal Fitness, Body Composition and Blood Parameters in Overweight Subjects
Source: ClinicalTrials.gov · Last updated 13 May 2026
Brief summary (registry, in English)
This study aims to evaluate the effects of a supervised whole-body high-intensity interval training (WB-HIIT) program on physical fitness and health outcomes in adults with overweight and obesity. WB-HIIT is a practical and time-efficient training modality based on body-weight exercises performed at high intensity with short recovery intervals. It may offer an accessible approach for improving health in individuals with excess body weight. Participants aged 18 to 55 years with a body mass index (BMI) between 25 and 35 kg/m² will take part in a supervised 10-week WB-HIIT program, performed in small groups and led by trained exercise professionals. Before and after the intervention, participants will undergo assessments including DXA-based body composition analysis, fasting blood sampling, muscular strength testing, a Chester step test, a maximal graded treadmill exercise test with gas-exchange analysis to determine VO₂peak, and functional evaluations (chair-stand, arm-curl, and 6-minute walk test). Physical activity and dietary intake will also be recorded. The primary objective of the study is to assess whether WB-HIIT improves cardiorespiratory fitness (VO₂peak) in adults with overweight. Secondary objectives include evaluating changes in muscular strength, body composition, metabolic markers, and functional capacity. The results may help determine whether an equipment-free WB-HIIT program can serve as an effective and accessible training approach for improving health and physical fitness in adults with overweight and obesity.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 19 Feb 2026
- Start date
- 9 Nov 2022
- Primary completion date
- Jun 2026
- Lead sponsor
- Université Libre de Bruxelles
- Diseases
- Obesity
- NCT number
- NCT07582718
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 9 Nov 2022 to the primary completion date, Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of any chronic medical condition other than overweight/obesity.
- Known cardiovascular, metabolic, respiratory, or musculoskeletal disease that contraindicates high-intensity exercise.
- Any condition judged by investigators to interfere with participation or data interpretation.
Other
- BMI \< 25 or \> 35 kg/m².
- Pregnancy.
- Inability to perform exercise testing or complete the WB-HIIT program.
Who the study is looking for
- Adults aged 18 to 55 years.
- Body mass index (BMI) between 25 and 35 kg/m².
- Able to provide written informed consent.
- Able to safely participate in high-intensity interval training.
- For participants with BMI \> 30 kg/m²: medical clearance from their general practitioner.
Age in the registry: 18 years to 55 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universite Libre de Bruxelles ULB - Coordinator of this site? Confirm its status | Brussels | Belgium | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.