NCT07582783Recruiting
A Study of Persistence to Guselkumab Treatment in Participants With Moderate-to-Severe Plaque Psoriasis in Romania
Persistence to Treatment With Guselkumab in Bio-Naive Patients With Moderate-to-Severe Plaque Psoriasis: A Romanian Non-Interventional Multi-center Observational Study
Source: ClinicalTrials.gov · Last updated 3 Nov 2026
Brief summary (registry, in English)
This study aims to assess the proportion of participants with moderate-to-severe plaque psoriasis who continue treatment with guselkumab over a two-year period.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 6 May 2026
- Start date
- 15 May 2026
- Primary completion date
- 15 Sept 2028
- Lead sponsor
- Janssen Research & Development, LLC
- Diseases
- Psoriasis
- NCT number
- NCT07582783
What you commit to
- Study type: Observational
- Planned participants: 200
- From 15 May 2026 to the primary completion date, 15 Sept 2028
- 20 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current or recent (in the last 30 days prior to first SC dose of guselkumab) participation in any interventional study with investigational product.
Other
- Meets any of the contraindications according to the latest version of the locally approved summary of product characteristics (SmPC)
- Is pregnant or lactating
- Currently enrolled in another observational study sponsored or managed by a Johnson \& Johnson company
Who the study is looking for
- Has a confirmed diagnosis of moderate-to-severe plaque psoriasis
- Participant must sign an informed consent form allowing source data verification in accordance with local requirements
- Is able to read, understand, and complete the patient reported outcomes (PRO) instruments in local language and comply with completion of all PRO instruments
- No previous exposure to biological treatment, including guselkumab (bio-naive patient)
- Intended for the treatment with guselkumab according to the approved indication
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (20)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mihaila G. Georgiana - Cabinet Medical Individual Dermatovenerologie Coordinator of this site? Confirm its status | Bârlad | Romania | Recruiting |
| Qualimed SRL Coordinator of this site? Confirm its status | Brasov | Romania | Recruiting |
| OptiDerm Estet Coordinator of this site? Confirm its status | Bucharest | Romania | Recruiting |
| Alin Nicolescu Medic Primar Dermato Venerologie Coordinator of this site? Confirm its status | Bucharest | Romania | Recruiting |
| Spitalul Clinic Colentina 1 Coordinator of this site? Confirm its status | Bucharest | Romania | Recruiting |
| Spitalul Clinic Colentina Coordinator of this site? Confirm its status | Bucharest | Romania | Recruiting |
| Spitalul Universitar de Urgenta Elias, Clinica de Cardiologie Coordinator of this site? Confirm its status | Bucharest | Romania | Recruiting |
| Spitalul Clinic Judetean de Urgenta Cluj-Napoca Coordinator of this site? Confirm its status | Cluj-Napoca | Romania | Recruiting |
| Ambulator Specialitate Sp Militar de Urgenta Dr Constantin Papilian Cluj Napoca Coordinator of this site? Confirm its status | Cluj-Napoca | Romania | Recruiting |
| Innovative Derm SRL Coordinator of this site? Confirm its status | Constanța | Romania | Recruiting |
| Policlinica Top Med Buna Vestire Coordinator of this site? Confirm its status | Craiova | Romania | Recruiting |
| Policlinica Dr.Corbeanu Coordinator of this site? Confirm its status | Craiova | Romania | Recruiting |
| MC Medica SRL Coordinator of this site? Confirm its status | Craiova | Romania | Recruiting |
| Derma Lux SRL Coordinator of this site? Confirm its status | Iași | Romania | Recruiting |
| Spitalul Clinic Judetean De Urgenta Bihor Coordinator of this site? Confirm its status | Oradea | Romania | Recruiting |
| Derma Lux SRL 1 Coordinator of this site? Confirm its status | Reghin | Romania | Recruiting |
| Evaderm Health SRL Coordinator of this site? Confirm its status | Slatina | Romania | Recruiting |
| Spitalul Judetean de Urgenta 'Sf.Ioan cel Nou', Sectia Oncologie Coordinator of this site? Confirm its status | Suceava | Romania | Recruiting |
| Clinica Cabimed Coordinator of this site? Confirm its status | Târgu-Mures | Romania | Recruiting |
| Dr Tirziu Dermato Chirurgie SRL Coordinator of this site? Confirm its status | Timișoara | Romania | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.