NCT07585344Completed
Interrupted 'Figure-of-X' Versus Continuous Suturing Technique for Abdominal Wall Closure in Colorectal Laparotomies
Interrupted 'Figure-of-X' Versus Continuous Suturing Technique for Abdominal Wall Closure in Colorectal Laparotomies: A Comparative Study on the Incidence of Burst Abdomen
Source: ClinicalTrials.gov · Last updated 26 May 2026
Brief summary (registry, in English)
This prospective randomized comparative study aims to evaluate whether interrupted figure-of-X fascial closure reduces the incidence of burst abdomen compared with continuous suturing in patients undergoing open colorectal laparotomy. Burst abdomen is a serious postoperative complication associated with increased morbidity, prolonged hospital stay, and reoperation. A total of 40 adult patients undergoing elective or emergency colorectal laparotomy will be randomized into two groups: interrupted figure-of-X closure or continuous fascial closure. The primary outcome will be the incidence of burst abdomen within 30 days after surgery. Secondary outcomes will include surgical site infection, seroma, hematoma, and length of hospital stay. The study is being conducted at the Department of General Surgery, Akbar Niazi Teaching Hospital, Islamabad, Pakistan.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 7 May 2026
- Start date
- 7 Nov 2025
- Primary completion date
- 5 Apr 2026
- Lead sponsor
- Islamabad Medical and Dental College
- Diseases
- Colorectal cancer
- NCT number
- NCT07585344
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 7 Nov 2025 to the primary completion date, 5 Apr 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with a previous midline laparotomy within the last 30 days.
Other illness
- Patients with known connective tissue disorders (e.g., Ehlers-Danlos syndrome) that might impair wound healing.
Other
- Patients in whom the abdominal wall is planned to be left open or managed with a temporary closure (open abdomen).
- Patients with an expected survival of less than 30 days.
- Emergency laparotomies.
Who the study is looking for
- Adult patients (aged 18 years and above).
- Patients undergoing open laparotomy for histologically confirmed colorectal cancer.
- Elective surgical procedures.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Islamabad Medical and Dental College Coordinator of this site? Confirm its status | Islamabad | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.