NCT07585695Not yet recruiting
Coronary Artery Disease Screening in Patients With Chronic Kidney Disease
Screening for Coronary Artery Disease in Patients With Chronic Kidney Disease
Source: ClinicalTrials.gov · Last updated 14 May 2026
Brief summary (registry, in English)
Patients with chronic kidney disease (CKD) have a markedly increased cardiovascular risk, with coronary artery disease being a leading cause of morbidity and mortality. Conventional cardiovascular risk scores and non-invasive diagnostic tests have limited accuracy in this population, partly due to atypical symptoms and frequent structural heart disease. Coronary flow reserve (CFR) is a key marker of coronary microvascular dysfunction and has strong prognostic value, but its assessment is usually limited to invasive techniques. Recent advances in cadmium-zinc-telluride single-photon emission computed tomography (CZT-SPECT) allow non-invasive measurement of CFR. The EVACKD study aims to evaluate the prognostic value of CFR assessed by CZT-SPECT in patients with CKD for predicting major adverse cardiovascular events over a 2-year follow-up.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 283 (estimated)
- First submitted
- 6 May 2026
- Start date
- Jun 2026
- Primary completion date
- Nov 2027
- Lead sponsor
- University Hospital, Grenoble
- NCT number
- NCT07585695
What you commit to
- Study type: Observational
- Planned participants: 283
- From Jun 2026 to the primary completion date, Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Legally protected adult (Article L1121-8 of the French Public Health Code)
- Person deprived of liberty (Article L1121-8 of the French Public Health Code)
- Pregnant woman
- Patient who has undergone a normal coronary exploration within the past year
Who the study is looking for
- Male or female patients aged over 18 years
- Affiliated with the French social security system
- Patients at renal risk based on albuminuria (Alb) and glomerular filtration rate (GFR \< 30 mL/min/1.73 m², or GFR \< 45 mL/min/1.73 m² with albuminuria \> 30 mg/g, or GFR \< 60 mL/min/1.73 m² with albuminuria \> 300 mg/g)
- Patients undergoing, independently of the research and according to the clinician's decision as part of standard care, CZT-SPECT myocardial perfusion imaging with coronary flow reserve measurement for cardiovascular risk assessment
- Having expressed no objection to participation in this study
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chu Grenoble Alpes Coordinator of this site? Confirm its status | La Tronche | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.