NCT07586501Enrolling by invitation
China-NINE Cohort:Neuroimmune Network in Elderly / Neurodegeneration
Source: ClinicalTrials.gov · Last updated 14 May 2026
Brief summary (registry, in English)
This is an observational study aimed at understanding the cognitive, functional, and behavioral characteristics of Chinese patients with cognitive impairment, exploring the underlying mechanisms, and providing evidence for early diagnosis, treatment, and care of cognitive disorders including dementia. Eligible participants will undergo a series of assessments and examinations, including cognitive and memory scale tests, routine blood tests, ApoE genetic testing, cerebrospinal fluid testing, brain MRI, functional MRI, and FDG-PET/AV45-PET scans when necessary. Additional samples such as saliva, nasal secretions, and stool may also be collected. Most evaluations are provided free of charge to support diagnosis and treatment guidance. Participation is voluntary. All personal information and research data will be kept confidential. Potential benefits include access to expert clinical care and free cognitive assessments for disease evaluation. Possible inconveniences include time commitment and temporary discomfort during examinations; medical support will be provided if needed.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 260 (estimated)
- First submitted
- 6 May 2026
- Start date
- 16 Jan 2026
- Primary completion date
- 1 Jan 2029
- Lead sponsor
- Yantai Yuhuangding Hospital
- Diseases
- Alzheimer disease, Parkinson disease
- NCT number
- NCT07586501
What you commit to
- Study type: Observational
- Planned participants: 260
- From 16 Jan 2026 to the primary completion date, 1 Jan 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Central nervous system infection, head trauma, epilepsy, multiple sclerosis, or other major neurological disorders.
- Malignant tumors. Family history of genetic disorders.
Who the study is looking for
- Participants with clinically diagnosed cognitive impairment. Patients with clinically diagnosed Parkinson's disease. Healthy control participants.
Age in the registry: 55 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Yantai Yuhuangding Hospital Coordinator of this site? Confirm its status | Yantai | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.