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NCT07586501Enrolling by invitation

China-NINE Cohort:Neuroimmune Network in Elderly / Neurodegeneration

Source: ClinicalTrials.gov · Last updated 14 May 2026

Brief summary (registry, in English)

This is an observational study aimed at understanding the cognitive, functional, and behavioral characteristics of Chinese patients with cognitive impairment, exploring the underlying mechanisms, and providing evidence for early diagnosis, treatment, and care of cognitive disorders including dementia. Eligible participants will undergo a series of assessments and examinations, including cognitive and memory scale tests, routine blood tests, ApoE genetic testing, cerebrospinal fluid testing, brain MRI, functional MRI, and FDG-PET/AV45-PET scans when necessary. Additional samples such as saliva, nasal secretions, and stool may also be collected. Most evaluations are provided free of charge to support diagnosis and treatment guidance. Participation is voluntary. All personal information and research data will be kept confidential. Potential benefits include access to expert clinical care and free cognitive assessments for disease evaluation. Possible inconveniences include time commitment and temporary discomfort during examinations; medical support will be provided if needed.

Status (registry)
Enrolling by invitation
Study type
Observational
Enrollment
260 (estimated)
First submitted
6 May 2026
Start date
16 Jan 2026
Primary completion date
1 Jan 2029
Lead sponsor
Yantai Yuhuangding Hospital
NCT number
NCT07586501

What you commit to

  • Study type: Observational
  • Planned participants: 260
  • From 16 Jan 2026 to the primary completion date, 1 Jan 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Central nervous system infection, head trauma, epilepsy, multiple sclerosis, or other major neurological disorders.
    • Malignant tumors. Family history of genetic disorders.

Who the study is looking for

  • Participants with clinically diagnosed cognitive impairment. Patients with clinically diagnosed Parkinson's disease. Healthy control participants.

Age in the registry: 55 years to 75 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Yantai Yuhuangding Hospital
Coordinator of this site? Confirm its status
YantaiChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.