NCT07589062Not yet recruiting
Healthy Eating and Active Living for People Living With Multiple Sclerosis (HEAL MS): A Lifestyle Program for People With Multiple Sclerosis
HEAL MS: A Culturally Adapted Lifestyle Medicine Intervention Targeting Metabolic and Immune Dysregulation in Multiple Sclerosis Using Multi-Omics Profiling
Source: ClinicalTrials.gov · Last updated 15 May 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn whether a structured lifestyle program can improve health and wellbeing in people living with multiple sclerosis (MS). The program focuses on four areas: nutrition, physical activity, sleep, and stress management. The study will also examine how lifestyle changes affect biological markers related to inflammation, metabolism, and immune function. The main questions the study aims to answer are: Can a 12-week lifestyle program improve fatigue, physical function, sleep, and quality of life in people with MS? Do lifestyle changes influence biological markers related to inflammation, metabolism, and mitochondrial function? Participants will first complete a 12-week observation period to measure their usual lifestyle and health. After this, they will take part in the 12-week HEAL MS lifestyle program. Participants will: Attend four assessment visits at Yas Clinic (baseline, before the intervention, after the intervention, and three months later) Participate in two supervised online exercise sessions per week during the 12-week program Follow a structured nutrition plan, with meals provided during the first two weeks Use a mobile application to log daily habits related to exercise, nutrition, sleep, and stress Complete questionnaires and physical tests and provide blood, saliva, and stool samples during assessment visits Researchers will analyze these data to understand whether lifestyle interventions can support symptom management and overall health in people living with MS.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 26 Mar 2026
- Start date
- 15 Apr 2026
- Primary completion date
- 15 Nov 2027
- Lead sponsor
- New York University Abu Dhabi
- Diseases
- Multiple sclerosis
- NCT number
- NCT07589062
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 15 Apr 2026 to the primary completion date, 15 Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concurrent enrollment in another lifestyle intervention
Other illness
- Significant cognitive impairment affecting app use and comprehension of the intervention
- Unmanaged psychiatric disorders
- Other immune-related or chronic inflammatory or metabolic diseases
Other
- MS relapse within the past 3 months
- Pregnancy or planned pregnancy
Who the study is looking for
- Confirmed MS diagnosis (McDonald criteria)
- EDSS score ≤ 6.5 (i.e., ambulatory with or without assistance)
- Stable disease-modifying therapy for ≥ 3 months
- Age 18-50
- Proficiency in English or Arabic
- Clearance to participate in a structured exercise program
- Ability to walk, sit and stand independently, and perform light-to-moderate movement patterns, even with modifications
- Ability and digital literacy to interact with the bilingual HEAL MS mobile app and
- Access to a computer for participation in online sessions
Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Yas Clinic Coordinator of this site? Confirm its status | Abu Dhabi | United Arab Emirates | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.