NCT07590362Recruiting
D-RSBI Versus RSBI for Predicting Weaning Success in COPD Patients
Diaphragmatic Rapid Shallow Breathing Index (D-RSBI) Versus Traditional Rapid Shallow Breathing Index (RSBI) for Prediction of Weaning Success From Mechanical Ventilation in COPD Patients
Source: ClinicalTrials.gov · Last updated 15 May 2026
Brief summary (registry, in English)
This prospective observational cohort study aims to compare the predictive accuracy of diaphragmatic rapid shallow breathing index (D-RSBI) versus traditional rapid shallow breathing index (RSBI) for predicting weaning success from invasive mechanical ventilation in COPD patients. Diaphragmatic ultrasound measurements will be performed during spontaneous breathing trials, and patients will be followed for 72 hours after extubation to assess weaning outcomes.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 7 May 2026
- Start date
- 15 Apr 2026
- Primary completion date
- 31 May 2027
- Lead sponsor
- Sohag University
- Diseases
- COPD
- NCT number
- NCT07590362
What you commit to
- Study type: Observational
- Planned participants: 100
- From 15 Apr 2026 to the primary completion date, 31 May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent major thoracic surgery.
Other illness
- Neuromuscular disease, phrenic nerve palsy, or diaphragmatic paralysis.
Other
- Refusal of consent
- Large pneumothorax or pathology interfering with ultrasound assessment.
- Terminal extubation.
- Poor sonographic window despite repeated attempts.
Who the study is looking for
- Mechanically ventilated COPD patients fulfilling standard weaning readiness criteria.
- Invasive mechanical ventilation for more than 24 hours before spontaneous breathing trial.
- Hemodynamically stable without significant vasopressor support.
- Adequate oxygenation with FiO2 ≤ 0.5 and PEEP ≤ 8 cmH2O .
- Preserved mental status and ability to initiate spontaneous breathing.
- Successful tolerance of spontaneous breathing trial conducted on CPAP mode with pressure support ≤ 8 cmH2O.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sohag University Hospital Coordinator of this site? Confirm its status | Sohag | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.