NCT07593196Recruiting
HER2-positive Metastatic Breast Cancer in Kazakhstan
A Multicenter Observational Retrospective Study of Therapeutic Approaches and Clinical Outcomes in Real Clinical Practice in Kazakhstan Patients With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
Planned study population consists of approximately 240 adult patients with HER2-positive mBC receiving anti-HER2 therapy in 12 oncological centers (in each center it is expected to recruit about 20 patients) in different regions in order to provide representative study sample. Patients will be included consecutively from the least recent diagnosis (within defined time period). Planned retrospective follow-up period for 1 patient is a period starting from the date of mBC diagnosis until end study or until patient's death, whichever occurs first. End of study will be at least 12 months after the latest date of mBC diagnosis to ensure all patients have the opportunity to contribute at least 12 months of data.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 240 (estimated)
- First submitted
- 12 May 2026
- Start date
- 12 Jun 2026
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- AstraZeneca
- Diseases
- Metastatic breast cancer
- NCT number
- NCT07593196
What you commit to
- Study type: Observational
- Planned participants: 240
- From 12 Jun 2026 to the primary completion date, 31 Dec 2026
- 9 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients received trastuzumab deruxtecan
Other illness
- Presence of other malignancies within the period from mBC diagnosis until the timepoint of data collection
Other
- The participation in any interventional trial within period since diagnosis until the end of study
Who the study is looking for
- Patients with HER2-positive mBC who are receiving or have started any anti-HER2 therapy (except for trastuzumab deruxtecan) at the time of inclusion
- The diagnosis of mBC was established between the 1st January 2022 to 31st December 2023
- Patients with the availability of at least 24 months of follow-up data (from the date of mBC diagnosis) in the medical records at the participating site, unless patient died/moved or refused the therapy within the first 24 months of diagnosis
- Age ≥18 years at the time of inclusion
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (9)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Research Site Coordinator of this site? Confirm its status | Aktobe | Kazakhstan | Not yet recruiting |
| Research Site Coordinator of this site? Confirm its status | Almaty | Kazakhstan | Recruiting |
| Research Site Coordinator of this site? Confirm its status | Astana | Kazakhstan | Recruiting |
| Research Site Coordinator of this site? Confirm its status | Karaganda | Kazakhstan | Recruiting |
| Research Site Coordinator of this site? Confirm its status | Oral | Kazakhstan | Recruiting |
| Research Site Coordinator of this site? Confirm its status | Petropavl | Kazakhstan | Recruiting |
| Research Site Coordinator of this site? Confirm its status | Semey | Kazakhstan | Recruiting |
| Research Site Coordinator of this site? Confirm its status | Shymkent | Kazakhstan | Not yet recruiting |
| Research Site Coordinator of this site? Confirm its status | Taraz | Kazakhstan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.