NCT07593313Recruiting
Treatment of Post-Stroke Central Pain
Efficacy and Safety of Short-Term Spinal Cord Stimulation Combined With Pharmacotherapy for Central Post-Stroke Pain: A Single-Center, Randomized, Controlled Trial
Source: ClinicalTrials.gov · Last updated 18 May 2026
Brief summary (registry, in English)
To evaluate the short-term analgesic efficacy of stSCS combined with pharmacotherapy compared with pharmacotherapy alone in patients with CPSP, measured by Numerical Rating Scale (NRS) score immediately after treatment.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- First submitted
- 26 Apr 2026
- Start date
- 1 Jan 2024
- Primary completion date
- 1 Aug 2026
- Lead sponsor
- Nanchong Central Hospital
- Diseases
- Stroke
- NCT number
- NCT07593313
What you commit to
- Study type: Interventional
- Planned participants: 80
- From 1 Jan 2024 to the primary completion date, 1 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of chronic pain before stroke
- Severe cognitive impairment that prevents cooperation with pain assessment (Mini-Mental State Examination, MMSE \< 15 points)
- Contraindications to spinal cord stimulation (SCS), such as coagulation disorders, active infections, or mental diseases that prevent cooperation
- Malignant tumors or other severe organic diseases with expected survival \< 1 year
Who the study is looking for
- Diagnosis of central post-stroke pain (CPSP) according to the International Association for the Study of Pain (IASP) criteria
- Clear history of stroke confirmed by cranial CT or MRI
- Pain occurring after stroke and distributed in body parts corresponding to central nervous system injury
- Pain with neuropathic characteristics (e.g., burning sensation, electric shock sensation, needle prick sensation)
- Pain not explained by other causes
- Age ≥ 18 years
- Pain duration ≥ 3 months
- Baseline pain Numerical Rating Scale (NRS) score ≥ 4 points
- Complete clinical data with follow-up time ≥ 6 months
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nanchong Central Hospital Coordinator of this site? Confirm its status | Nanchong | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.