NCT07595081Completed
Propionic Acid for Multiple Sclerosis: Safety and Benefits
Propionic Acid in Multiple Sclerosis: Safety, Tolerability and Clinical Outcomes From the Pro-MADAI Study
Source: ClinicalTrials.gov · Last updated 22 Sept 2026
Brief summary (registry, in English)
The purpose of this study is to explore the long-term safety, tolerability, and clinical efficacy of propionic acid as an add-on therapy in multiple sclerosis (MS).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 22 (actual)
- First submitted
- 3 May 2026
- Start date
- 1 Aug 2024
- Primary completion date
- 1 May 2025
- Lead sponsor
- Salzburger Landeskliniken
- Diseases
- Multiple sclerosis
- NCT number
- NCT07595081
What you commit to
- Study type: Interventional
- Participants enrolled: 22
- From 1 Aug 2024 to the primary completion date, 1 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of ongoing propionic acid (PA) supplementation exceeding 3 months
- Presence of severe active systemic disease
- Presence of acute neurological conditions
Other
- Positive JC virus titer during natalizumab treatment
Who the study is looking for
- Diagnosis of multiple sclerosis (MS)
- Clinically and radiologically stable MS in the previous 3 months
- Age between 18 and 70 years
- Positive finding for oligoclonal bands (OCBs)
- Written consent
- Blood collection at the beginning and end of the study for routine parameter examination as well as sample preservation (especially for measuring propionic acid levels)
- Negative pregnancy test for female participants of childbearing age
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Salzburger Landeskliniken Coordinator of this site? Confirm its status | Salzburg | Austria | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.