NCT07595809Recruiting
Dietary Intervention and Physical Activity in Patients With Heart Failure and Reduced Ejection Fraction
Source: ClinicalTrials.gov · Last updated 19 May 2026
Brief summary (registry, in English)
Heart failure with reduced ejection fraction (HFrEF) is frequently associated with abnormalities in body composition, including reduced skeletal muscle mass and sarcopenia, which are independent predictors of reduced exercise tolerance, impaired quality of life, and increased mortality. Despite advances in pharmacological therapy, evidence-based non-pharmacological strategies aimed at preventing muscle mass loss remain limited. This randomized controlled trial aims to evaluate the effects of dietary intervention based on the DASH diet with high-protein elements, resistance exercise training, and their combination on skeletal muscle mass, functional capacity, echocardiographic parameters, biochemical markers, and quality of life in patients with HFrEF.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 13 May 2026
- Start date
- 8 May 2023
- Primary completion date
- 31 Jul 2026
- Lead sponsor
- Medical University of Silesia
- Diseases
- Heart failure
- NCT number
- NCT07595809
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 8 May 2023 to the primary completion date, 31 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- NYHA functional class IV heart failure Potentially reversible cause of heart failure Estimated glomerular filtration rate \<30 mL/min Severe anemia (hemoglobin \<9 g/dL) Uncontrolled thyroid disease Severe hepatic dysfunction History of hyperkalemia or hyperkalemia at baseline Epilepsy Presence of joint endoprostheses Gastrointestinal disorders limiting adherence to the DASH diet Physical limitations precluding participation in structured exercis
Who the study is looking for
- Written informed consent obtained prior to participation Age \>30 years Diagnosis of chronic heart failure, NYHA functional class I-III Left ventricular ejection fraction \<40%
Age in the registry: 30 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| 2nd Department and Clinical Ward of Cardiology Specialist Hospital in Zabrze, Poland Coordinator of this site? Confirm its status | Zabrze | Poland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.