NCT07597291Recruiting
Cardiovascular Outcomes Registry in Cardiogenic SHOCK (COR-SHOCK)
Cardiovascular Outcomes Registry in Cardiogenic SHOCK
Source: ClinicalTrials.gov · Last updated 11 Jun 2026
Brief summary (registry, in English)
The goal of this observational study is to evaluate the clinical outcomes and management approaches of cardiogenic shock throughout the years in adult patients admitted to a Cardiology Department. The main questions it aims to answer are: * How have management strategies and clinical outcomes for cardiogenic shock evolved over time? * How do clinical, laboratory, and advanced hemodynamic monitoring parameters relate to patient survival and overall prognosis in this population? Researchers will evaluate clinical data collected from 2017 onwards to see if therapeutic advancements and changes in clinical management over the years have led to improved patient survival and quality of care. Participants will: * Receive standard, routine medical care for cardiogenic shock as determined by their clinical team (no experimental interventions will be introduced). * Have their clinical, laboratory, and imaging data collected from hospital electronic records during their stay. * Be followed for up to 1 year after hospital admission to evaluate long-term survival and clinical outcomes.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 800 (estimated)
- First submitted
- 9 May 2026
- Start date
- 10 Jun 2026
- Primary completion date
- 31 Dec 2036
- Lead sponsor
- Hospital de Santa Cruz, Portugal
- Diseases
- Coronary artery disease
- NCT number
- NCT07597291
What you commit to
- Study type: Observational
- Planned participants: 800
- From 10 Jun 2026 to the primary completion date, 31 Dec 2036
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Age \< 18 years.
Other
- Other primary etiologies of shock at presentation (e.g., hypovolemic, hemorrhagic, septic, obstructive shock due to acute pulmonary embolism, or anaphylactic shock).
- Refusal to participate in the study (applicable only to the prospective cohort).
Who the study is looking for
- -Cardiogenic shock according to the following criteria:
- Cardiac disorder resulting in hypotension, defined as at least one of the following:
- Systolic blood pressure (SBP) \<90 mmHg for ≥30 minutes, or
- Requirement for vasopressors, inotropes, or mechanical circulatory support to maintain SBP ≥90 mmHg
- AND
- Evidence of tissue hypoperfusion, defined by the presence of at least one of the following:
- Serum lactate \>2 mmol/L
- Acute kidney injury and/or oliguria
- Acute hepatic injury
- Cool or mottled extremities
- Altered mental status
- AND
- Clinical presentation judged to be primarily attributable to a cardiac etiology.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Unidade Local de Saúde de Lisboa Ocidental Coordinator of this site? Confirm its status | Carnaxide | Portugal | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.