NCT07597330Completed
POD Risk for Colorectal Cancer Surgery
A Novel Risk System Integrating Clustering-derived Subtype and TyG Index for Predicting Postoperative Delirium in Colorectal Cancer Patients
Source: ClinicalTrials.gov · Last updated 19 May 2026
Brief summary (registry, in English)
Postoperative delirium is a common complication after colorectal cancer surgery that hinders recovery. This observational study hypothesizes that a simple, practical risk tool can be developed by combining preoperative clinical conditions, blood tests (including the TyG index), and clinical subtypes identified via clustering analysis. Investigators will enroll patients undergoing elective colorectal cancer surgery, assess delirium twice daily for 7 days postoperatively using the 3D-CAM, and finalize the scoring scale. It will help doctors quickly identify high-risk patients for targeted care to improve recovery. Only data will be collected; patients receive standard clinical treatment.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 590 (actual)
- First submitted
- 13 Jan 2026
- Start date
- 1 Jan 2024
- Primary completion date
- 1 Jun 2025
- Lead sponsor
- LanZhou University
- Diseases
- Colorectal cancer
- NCT number
- NCT07597330
What you commit to
- Study type: Observational
- Participants enrolled: 590
- From 1 Jan 2024 to the primary completion date, 1 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Emergency surgery or palliative surgery (non-curative resection);
Other illness
- Postoperative pathology confirmed non-malignant tumor;
- Presence of visual, cognitive, language, or speech impairment; or history of neuropsychiatric diseases (dementia, Parkinson's disease, cerebrovascular accidents);
Age
- Age ≥90 years old;
Other
- No preoperative cognitive function assessment or MMSE score \<18;
- Postoperative admission to intensive care unit (ICU) (excluded due to different monitoring and intervention patterns);
- Missing key data \>5% (e.g., incomplete TyG index calculation, missing clustering analysis variables);
- Refusal to participate or inability to complete 7-day postoperative follow-up.
Who the study is looking for
- Histologically confirmed colorectal cancer (colon or rectal cancer) via - preoperative or postoperative pathology;
- Scheduled for elective surgical intervention (open or laparoscopic resection);
- Preoperative Mini Mental State Examination (MMSE) score ≥18 (no pre-existing cognitive impairment);
- Able to provide written informed consent (self or legal representative);
- Complete preoperative clinical and laboratory data.
Age in the registry: 18 years to 89 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Hospital of Lanzhou University Coordinator of this site? Confirm its status | Lanzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.