NCT07598071Completed
A Comparison of Single-Stage Full-Mouth Disinfection With Quadrant-Based Scaling and Root Planing in Patients With Uncontrolled Type 2 Diabetes and Severe Periodontitis: An Assessment of Its Impact on Quality of Life
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
This study evaluated the effects of a single-stage full mouth disinfection (FMD) protocol versus a quadrant-based tooth surface cleaning and root planing (Q-SRP) protocol on changes in clinical periodontal parameters over a 3-month period, as well as on the social, psychological and functional well-being of patients with poorly controlled type 2 diabetes and severe periodontitis.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 82 (actual)
- First submitted
- 12 May 2026
- Start date
- 13 Nov 2024
- Primary completion date
- 3 Mar 2026
- Lead sponsor
- Pamukkale University
- Diseases
- Type 2 diabetes
- NCT number
- NCT07598071
What you commit to
- Study type: Interventional
- Participants enrolled: 82
- From 13 Nov 2024 to the primary completion date, 3 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients receiving systemic antibiotic therapy during the same period
- Patients undergoing hormone therapy
- Individuals who had used antibiotics or anti-inflammatory drugs regularly during the 3-month period following the start of the study
Other illness
- Patients with a history of acute or chronic infection within the past 6 months
- İndividuals with medical or psychological conditions that could affect the accurate understanding and completion of the questionnaires
Lab values
- Patients using non-steroidal anti-inflammatory drugs, phenytoin, calcium channel blockers or cyclosporine
Other
- Individuals who were pregnant or breastfeeding
- Patients who had undergone periodontal treatment within the past 6 months
- Smokers
Who the study is looking for
- Individuals with poorly controlled diabetes and HbA1c levels between 7% and 9%
- At least 15 natural teeth and, from a periodontal perspective: probing pocket depth (PPD) ≥ 6 mm, clinical attachment loss (CAL) ≥ 5 mm, radiographic bone loss extending to the middle or apical third of the root, and periodontitis-related tooth loss of ≤ 4 in different quadrants
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Pamukkale University Coordinator of this site? Confirm its status | Denizli | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.