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NCT07598695RecruitingEarly phase 1

Sensory Feedback and Hand Motor Adaptation

Impact of Altered Sensory Feedback on Adaptation of Hand Muscle Coordination of Stroke Survivors

Source: ClinicalTrials.gov · Last updated 22 May 2026

Brief summary (registry, in English)

The following experiment will be conducted with 15 chronic stroke survivors and 15 control subjects. Subjects will perform hand movements in the virtual reality environment using a head-mounted display. Quest's onboard cameras allow real-time tracking of hand motion, estimating joint angles of the finger and the thumb. For each feedback manipulation condition (i.e., movement amplification or reduction), the estimated joint angles will be multiplied by a factor greater than 1 (amplification) or a factor smaller than 1 (reduction). Then the newly-estimated hand posture will be displayed in the VR environment. Subjects will be randomly assigned into two groups (A and B), who will receive the assistance in a different order. Subjects will perform finger extension under three conditions: no sensory modulation, movement visual feedback (VF) amplification, and movement VF reduction (error augmentation), while their movement muscle activation patterns are recorded.

Status (registry)
Recruiting
Phase (registry)
Early phase 1
Study type
Interventional
Enrollment
30 (estimated)
First submitted
5 May 2026
Start date
1 Oct 2025
Primary completion date
1 Oct 2026
Lead sponsor
The Catholic University of America
Diseases
Stroke
NCT number
NCT07598695

What you commit to

  • Study type: Interventional · Early phase 1
  • Planned participants: 30
  • From 1 Oct 2025 to the primary completion date, 1 Oct 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Presence of concurrent severe medical illness

Other illness

  • Musculoskeletal injuries (e.g., fracture) or medical complications (e.g., severe cardiovascular disease).

Other

  • Pain in hand or arm with movements
  • Loss of voluntary control of fingers and thumb
  • Inability to provide informed consent

Who the study is looking for

  • Age: 20 - 70 years old
  • First-ever unilateral cortical stroke with resultant hemiparesis at least 6 months prior to the experimental testing
  • Fugl-Meyer Upper Extremity Section 31 - 55

Age in the registry: 20 years to 70 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Catholic University of America
Coordinator of this site? Confirm its status
Washington D.C.United StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.