NCT07598773Enrolling by invitation
BETA: Study in Prediabetes Type 2 Diabetes
Beta-cell Evaluation Through Data-driven Assessments (BETA): Study in Prediabetes Type 2 Diabetes
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
This study is testing the feasibility of using non-invasive, remote digital tools including continuous glucose monitors (CGMs) and the Oura Ring to predict the function of beta-cells, the cells in the pancreas that secrete insulin. This study is being done in individuals with prediabetes or Type 2 diabetes. The aim is to develop remote digital tools that can predict the health and functioning of the pancreas in people with prediabetes or Type 2 diabetes, allowing personalized treatment approaches to preserve insulin secretion.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 130 (estimated)
- First submitted
- 14 May 2026
- Start date
- 25 Mar 2026
- Primary completion date
- 1 Feb 2027
- Lead sponsor
- 4YouandMe
- Diseases
- Type 2 diabetes
- NCT number
- NCT07598773
What you commit to
- Study type: Observational
- Planned participants: 130
- From 25 Mar 2026 to the primary completion date, 1 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Using any of the following medications: Glucocorticoids, Non-Selective Beta Blockers (e.g., propranolol), Thiazide Diuretics
- Currently using tobacco products (cigarettes, vapes, chew, dip, etc.)
Other illness
- Dairy or soy allergy
- Diagnosed with Type 1 diabetes or MODY (Maturity-Onset Diabetes of the Young)
- History of pancreatic disease (other than diabetes) or pancreatic transplantation
- Have any active malignancy within the last 12 months
Lab values
- History of bariatric / other gastrointestinal surgery anticipated to affect glucose metabolism / cause gastroparesis
- History of systemic disease (hepatic, cardiovascular, other) likely to interfere with glucose metabolism or study participation
Other
- Using any Abbott CGM (prescribed or OTC)
- BMI \<18 kg/m2 or \>40 kg/m2
- Currently pregnant or breastfeeding
- Using an insulin pump
- Hospitalized overnight for any reason in the last 3 months
Who the study is looking for
- 18+ years old
- Have an established diagnosis of Prediabetes or Type 2 diabetes
- Have a glycated hemoglobin (HbA1c) below 8% (64 mmol/mol) and a body mass index (BMI) between 18-40 kg/m2 that will be determined from your height and weight
- Are willing to use an Abbott FreeStyle Libre 3/3+ Continuous Glucose Monitor (CGM) supplied by the study and provide the study investigators access to the CGM data
- Are willing to use the study wearable devices (e.g., Oura Ring)
- Are able to read, write, and speak in English
- If you use long-acting insulin, you must be on a prescribed regimen where you administer it at bedtime only and no other time of day (bolus short-acting may be used at any time as needed)
- All medication regimens must have a minimum of 30 days supply, and no new medications started within 30 days of enrollment
- Weight must be stable (± 10 pounds) for 2 months prior to enrollment
- Must have a personally owned iPhone 6s or newer (iOS 16.4+) or Android smartphone (version 12 or newer) and use this phone to download and use the study app and use the provided study devices
- Must have a personally owned computer or tablet or have access to these devices at home
- Must reside in the North San Francisco Bay area and be willing to travel to Novato, CA to attend two morning clinic assessments at the Buck Institute
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Buck Institute for Research on Aging Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.