NCT07599228Not yet recruiting
Using Virtual Reality to Teach Mindfulness to People With Migraine
Migraine Intervention Using Reality-Assisted Guided Experience
Source: ClinicalTrials.gov · Last updated 30 Sept 2026
Brief summary (registry, in English)
The aim of this clinical trial is to learn if people with migraine can learn a type of biobehavioral therapy called Acceptance and Commitment Therapy (ACT) by using a virtual reality headset. Researchers are studying if this type of mindfulness therapy helps to decrease migraine-related disability. Participants will be randomized to treatment as usual or active virtual reality groups for four weeks. Everyone will keep symptom diaries, complete surveys, attend two clinic visits, and have two blood draws.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 160 (estimated)
- First submitted
- 28 Apr 2026
- Start date
- 30 Sept 2026
- Primary completion date
- 31 Aug 2029
- Lead sponsor
- Brigham and Women's Hospital
- Diseases
- Migraine
- NCT number
- NCT07599228
What you commit to
- Study type: Interventional
- Planned participants: 160
- From 30 Sept 2026 to the primary completion date, 31 Aug 2029
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Medication overuse (\>10 days/month)
Other illness
- Active psychiatric or neurological comorbidities
- Significant visual/hearing/mobility impairment affecting VR use
Other
- Vertigo/vestibular dysfunction
- Pregnancy, breastfeeding or planning pregnancy within study timeframe
Who the study is looking for
- Adults aged 18-80
- Diagnosed with episodic migraine and experience 4-10 migraine days/month
- On a stable dose of CGRP mAb for three months prior
- Satisfy 4 week run-in of 4-10 headaches/month
- Not taking other preventive medications
- Not pregnant, breastfeeding, or planning to become pregnant within study timeframe
- Able and willing to use VR device
- No history of significant psychiatric illness
- Willing to comply with study procedures
- English-speaking
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Brigham and Womens Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Brigham and Women's Health Care Center Coordinator of this site? Confirm its status | Chestnut Hill | United States | Unknown status |
| Brigham and Women's Hospital Coordinator of this site? Confirm its status | Chestnut Hill | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.