NCT07599501Not yet recruiting
Nutritional Supplementation to Improve Colorectal Cancer Surgery
Perioperative Nutritional Supplementation to Prevent Postoperative Complications and Improve Postoperative Outcomes After Colorectal Cancer Surgery: a Single-center Unblinded Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
This study aims to explore the effectiveness of perioperative Oral Nutritional Supplementation (ONS) combined with an optimized, tailored diet in reducing the risk of postoperative complications and improving the nutritional status of colorectal cancer patients scheduled for curative colorectal resection.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 190 (estimated)
- First submitted
- 4 May 2026
- Start date
- 30 Sept 2026
- Primary completion date
- 28 Feb 2028
- Lead sponsor
- Istituto Clinico Humanitas
- Diseases
- Colorectal cancer
- NCT number
- NCT07599501
What you commit to
- Study type: Interventional
- Planned participants: 190
- From 30 Sept 2026 to the primary completion date, 28 Feb 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Participants aged more than 18 years old.
- Histological diagnosis of colorectal adenocarcinoma.
- Participants scheduled for elective minimally invasive colorectal resection.
- Participants with a preoperative MUST score equal to or below 2. Exclusion criteria
- Any condition that, in the opinion of the investigator, may interfere with the study procedures.
- Emergent surgery.
- Planned open surgery. Participants undergoing unplanned surgical conversion (from minimally invasive to open) will be withdrawn from the study.
- Any concomitant surgery unrelated to the primitive colorectal cancer (for example, concomitant liver metastasis resection).
- Participants with preoperative MUST score \> 2.
- Pregnant or breastfeeding participants. Women of childbearing potential must agree to use a reliable contraceptive method. Otherwise, a pregnancy urine test must be performed at each study visit to exclude a potential pregnancy.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IRCCS Humanitas Research Hospital Coordinator of this site? Confirm its status | Rozzano | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.