NCT07600398Active, not recruiting
ReDS-Guided Decongestion in Acute Heart Failure (ReDS-LATAM HF)
ReDS-LATAM HF: A Randomized Trial of Remote Dielectric Sensing-Guided Decongestion in Acute Heart Failure
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
Heart failure (HF) is a leading cause of hospitalization, with high rates of early readmission largely driven by residual congestion at discharge. Conventional methods to assess congestion are often imprecise and may fail to guide optimal decongestive therapy. Remote Dielectric Sensing (ReDS) is a non-invasive technology that provides a rapid and objective estimate of lung fluid content. This study aims to evaluate whether a ReDS-guided decongestion strategy improves clinical outcomes compared with standard care in patients hospitalized for acute heart failure. In this randomized controlled trial, patients will be assigned 1:1 to a ReDS-guided strategy or standard care. ReDS measurements will be performed in both groups but will only guide treatment in the intervention arm. The primary endpoint is a composite of all-cause mortality, heart failure rehospitalization, or unplanned HF visit within 30 (±5) days after discharge.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 216 (estimated)
- First submitted
- 14 May 2026
- Start date
- 1 May 2026
- Primary completion date
- 1 Jun 2027
- Lead sponsor
- Instituto Cardiovascular de Buenos Aires
- Diseases
- Heart failure
- NCT number
- NCT07600398
What you commit to
- Study type: Interventional
- Planned participants: 216
- From 1 May 2026 to the primary completion date, 1 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- Need for inotropes, vasopressors, or mechanical circulatory support at enrollment Heart transplant recipient Mechanical ventilation at enrollment Conditions that prevent reliable ReDS measurement Planned cardiac surgery or intervention during the study period Severe renal dysfunction (eGFR \<15 mL/min/1.73 m² or dialysis) Life expectancy \<3 months Inability to complete follow-up Participation in another interventional trial Any condition that may compromise safety or study integrity
Who the study is looking for
- Age ≥21 years
- Hospitalization for acute heart failure with signs of congestion within 48 hours of admission
- Elevated natriuretic peptides (NT-proBNP \>1000 pg/mL or BNP equivalent)
- Ability to provide informed consent
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Instituto Cardiovascular de Buenos Aires Coordinator of this site? Confirm its status | Buenos Aires | Argentina | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.