NCT07600411Recruiting
Binge Eating, Depression and Anxiety Outcomes After Sleeve Gastrectomy Versus Gastric Bypass: A Cohort Study
Binge Eating, Depression and Anxiety Outcomes Following Laparoscopic Sleeve Gastrectomy Versus Roux-en-Y or One-Anastomosis Gastric Bypass: A Prospective Cohort Study
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if the type of weight-loss surgery (sleeve gastrectomy or gastric bypass) affects binge eating, depression, and anxiety in adults with severe obesity. The main questions it aims to answer are: Does sleeve gastrectomy lead to different changes in binge eating compared with gastric bypass? Does the type of surgery lead to different changes in depression and anxiety symptoms? Researchers will compare people who have sleeve gastrectomy with those who have gastric bypass to see if there are differences in binge eating, depression, and anxiety levels up to 12 months after surgery. Participants will: Complete questionnaires about eating habits, mood, anxiety, general health, and body image before surgery. Undergo either a sleeve gastrectomy or a gastric bypass operation (both are standard care). Follow a standard post-surgery diet plan. Attend follow-up visits at 1 week, 2 weeks, 1 month, and then monthly for 12 months, where they will complete the same questionnaires again.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 15 May 2026
- Start date
- 11 Mar 2026
- Primary completion date
- 30 Sept 2027
- Lead sponsor
- Cairo University
- Diseases
- Obesity
- NCT number
- NCT07600411
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 11 Mar 2026 to the primary completion date, 30 Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Contraindication to surgery: American Society of Anesthesiologists (ASA) class IV or higher
- History of receiving radiotherapy or chemotherapy for cancer treatment
- Previous bariatric surgery (revisional surgery excluded)
Other illness
- Active substance use disorder or uncontrolled severe psychiatric illness that would impair ability to comply with study procedures (e.g., active psychosis, severe suicidal ideation)
- Untreated thyroid disorder (e.g., hypothyroidism or hyperthyroidism)
Age
- Age \< 18 years or \> 60 years
Other
- Inability or unwillingness to adhere to postoperative lifestyle changes
- Pregnant or breastfeeding women (pregnancy test performed preoperatively per institutional protocol)
Who the study is looking for
- Age between 18 and 60 years
- Body Mass Index (BMI) ≥ 35 kg/m² without comorbidities, OR BMI ≥ 30 kg/m² with at least one obesity-related medical comorbidity (e.g., type 2 diabetes, hypertension, obstructive sleep apnea, dyslipidemia)
- Patient is generally fit for laparoscopic surgery and general anesthesia as determined by preoperative evaluation
- Patient agrees to comply with postoperative lifestyle changes (dietary modifications and follow-up schedule)
- Willing and able to provide written informed consent
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of Medicine Cairo University Coordinator of this site? Confirm its status | Cairo | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.