NCT07601724Recruiting
The Impact of Volume Overload on Obstructive Sleep Apnea in Patients With Congestive Heart Failure
Source: ClinicalTrials.gov · Last updated 22 May 2026
Brief summary (registry, in English)
The goal of this observational study is to learn how removing extra fluid from the body (diuresis) affects sleep apnea in adults hospitalized with heart failure. The main questions it aims to answer are: Does sleep apnea severity improve after fluid removal? Is the improvement in sleep apnea related to the amount of fluid removed? Do changes in neck size reflect changes in sleep apnea severity? Participants admitted to the hospital with heart failure and fluid overload will take part in this study. Participants will: Use a wearable sleep monitoring device (WatchPAT) on the first night of hospitalization Use the device again after fluid removal, when the treating cardiologist determines that the patient is no longer fluid overloaded Have their neck circumference measured before and after fluid removal Have their weight and fluid balance recorded during hospitalization Have routine blood tests and clinical assessments as part of standard care Researchers will compare each participant's results before and after fluid removal to see if sleep apnea improves and whether these changes are linked to fluid removal and changes in neck circumference.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 15 Apr 2026
- Start date
- 1 Jan 2026
- Primary completion date
- Jan 2027
- Lead sponsor
- Itshak Amsalem
- Diseases
- Heart failure
- NCT number
- NCT07601724
What you commit to
- Study type: Observational
- Planned participants: 50
- From 1 Jan 2026 to the primary completion date, Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current treatment with continuous positive airway pressure (CPAP)
Other illness
- Acute respiratory failure requiring mechanical ventilation
- Conditions preventing proper use of the WatchPAT device (e.g., severe hand or finger injury)
Other
- Known central sleep apnea as the predominant sleep-disordered breathing type
- Hemodynamic instability precluding participation
- Pregnancy
Who the study is looking for
- Adults aged 18 years or older
- Hospitalized with decompensated heart failure and clinical evidence of fluid overload
- Diagnosis of heart failure (reduced or preserved ejection fraction)
- Clinically indicated for diuretic therapy
- Able to undergo sleep apnea assessment using the WatchPAT device
- Able to provide informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shaare Zedek Medical Center Coordinator of this site? Confirm its status | Jerusalem | Israel | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.