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NCT07602192Recruiting

Quantitative Chest CT and Multi-Omics to Distinguish Asthma From COPD and Predict Treatment Response

Prospective Multicenter Cohort to Discriminate Asthma Versus Chronic Obstructive Pulmonary Disease and Predict Treatment Response Using Quantitative Chest CT and Multi-Omics

Source: ClinicalTrials.gov · Last updated 7 Jul 2026

Brief summary (registry, in English)

This study aims to improve the diagnosis and treatment prediction of asthma and chronic obstructive pulmonary disease (COPD) by combining quantitative chest computed tomography (CT) imaging with multi-omics data. Adults with asthma or COPD will be enrolled and undergo routine clinical evaluations, pulmonary function tests, blood tests, and chest CT scans. Additional samples, such as sputum and microbiome specimens, may also be collected. No experimental drugs or devices will be administered as part of this study. Researchers will analyze CT imaging features together with clinical, laboratory, and biological data to better distinguish asthma from COPD and to identify factors that may predict treatment response. The findings are expected to contribute to more precise and personalized management of chronic airway diseases.

Status (registry)
Recruiting
Study type
Observational
Enrollment
200 (estimated)
First submitted
22 Feb 2026
Start date
22 Dec 2025
Primary completion date
30 Nov 2027
Lead sponsor
Korea University Guro Hospital
Diseases
Asthma, COPD
NCT number
NCT07602192

What you commit to

  • Study type: Observational
  • Planned participants: 200
  • From 22 Dec 2025 to the primary completion date, 30 Nov 2027
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Acute exacerbation or active lower respiratory tract infection (e.g., pneumonia) within the past 4 weeks
  • Inability to undergo chest CT (e.g., poor cooperation or severe medical condition)

Other

  • Pregnancy or breastfeeding
  • Refusal to consent to study procedures

Who the study is looking for

  • Age ≥19 years
  • COPD group: post-bronchodilator FEV1/FVC \< 0.70
  • Asthma group: clinically confirmed diagnosis of asthma by a physician
  • Able to provide voluntary written informed consent

Age in the registry: 19 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
SMG-SNU Boramae Medical Center
Coordinator of this site? Confirm its status
SeoulSouth KoreaRecruiting
Korea University Guro Hospital
Coordinator of this site? Confirm its status
SeoulSouth KoreaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.