NCT07602361Active, not recruiting
Genetic Markers Associated With Capsaicinoid Supplementation Effects in Overweight and Obesity
Identification of Genetic Markers Associated With the Effects of Capsaicinoid Supplementation on Appetite, Body Composition, Metabolic Profile, and Inflammatory Markers in Individuals With Overweight or Obesity
Source: ClinicalTrials.gov · Last updated 22 May 2026
Brief summary (registry, in English)
Capsaicinoids, compounds found in chili peppers of the genus Capsicum, are responsible for their spiciness and may have potential benefits in weight control and cardiometabolic health. They act on processes such as appetite regulation, fat burning, inflammation, and metabolism, although their effects vary among individuals, possibly due to genetic factors. In Mexico, where chili consumption is high and obesity is a significant public health problem, it is particularly relevant to study these genetic variations. The proposed research aims to identify genetic markers that can predict the response to capsaicinoid supplementation and thus develop personalized nutritional strategies for the treatment of obesity and its complications.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 5 May 2026
- Start date
- 22 Apr 2026
- Primary completion date
- 26 Aug 2026
- Lead sponsor
- Universidad Autonoma de Baja California
- Diseases
- Obesity
- NCT number
- NCT07602361
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 22 Apr 2026 to the primary completion date, 26 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of hypocaloric diets or weight-loss medications within the three months prior to study initiation
Other illness
- History of thyroid or metabolic disorders requiring pharmacological treatment, such as diabetes mellitus or coronary heart disease
- Known hypersensitivity to capsaicinoids
- Gastrointestinal disorders, such as ulcerative colitis or irritable bowel syndrome
Other
- Pregnant or breastfeeding women
- Active smokers
- High alcohol consumption, defined as \>20 g/day in women and \>40 g/day in men
- Daily chili consumption or high habitual intake of capsaicinoids
Who the study is looking for
- Adults diagnosed with overweight or obesity within the age range established for the study
- Willingness to participate in the study
- Signed informed consent form
Age in the registry: 25 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universidad Autónoma de Baja California Coordinator of this site? Confirm its status | Tijuana | Mexico | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.