NCT07602803Completed
The Effect of GLP1 Agonists on Weight Loss in BBS Cohort in the UK
GLP1 Agonists Once Weekly for the Treatment of Obesity in Patients With Bardet-Biedl Syndrome (BBS)
Source: ClinicalTrials.gov · Last updated 27 May 2026
Brief summary (registry, in English)
The goal of this observational study is to learn about the long-term effects of GLP1 agonists (weight loss jab, including Mounjaro) in patients with Bardet-Biedl Syndrome (BBS) who take GLP1 agonists to treat high body weight. The main question: Do GLP1 agonists effectively and safely lower body weight in patients with BBS when taken long-term, compared to patients not on these medications? The investigators look at the change (%) in weight during the observational periods.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 300 (actual)
- First submitted
- 15 May 2026
- Start date
- 1 Jan 2023
- Primary completion date
- 1 Apr 2026
- Lead sponsor
- The Queen Elizabeth Hospital
- Diseases
- Obesity
- NCT number
- NCT07602803
What you commit to
- Study type: Observational
- Participants enrolled: 300
- From 1 Jan 2023 to the primary completion date, 1 Apr 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Adult patients with a genetic diagnosis of BBS under the national BBS centres (London and Birmingham in the UK) who lost follow ups or significant missing data, or BMI\<30 in patients without GLP1 agonists.
Who the study is looking for
- All the adult patients with a genetic diagnosis of BBS under the national BBS centres (London and Birmingham in the UK).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Queen Elizabeth Hospital Birmingham Coordinator of this site? Confirm its status | Birmingham | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.