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NCT07603583Recruiting

Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension

The Exploration of the Relationship Between Hypertension and Sleep Apnea Through Heart Rate Variability, and the Subsequent Investigation of Non-pharmacological and Pharmacological Treatments

Source: ClinicalTrials.gov · Last updated 22 May 2026

Brief summary (registry, in English)

This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function. Hypertensive patients at high risk for OSA will undergo 24-hour Holter electrocardiogram monitoring to assess HRV parameters, along with overnight polysomnography (PSG) to determine OSA severity. The study will analyze the association between HRV indices and the apnea-hypopnea index (AHI), and develop predictive models using machine learning techniques. In addition, patients diagnosed with OSA will be followed after treatment, and changes in HRV and blood pressure will be evaluated to assess treatment effects and autonomic function recovery. The results of this study may provide a cost-effective and clinically applicable approach for early detection, risk stratification, and management of OSA in patients with hypertension.

Status (registry)
Recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
18 May 2026
Start date
Apr 2026
Primary completion date
Dec 2026
Lead sponsor
Kaohsiung Armed Forces General Hospital
NCT number
NCT07603583

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From Apr 2026 to the primary completion date, Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Unstable medical condition that may interfere with study participation

Other

  • Refusal to undergo HRV monitoring or polysomnography
  • Inability to comply with study procedures

Who the study is looking for

  • Age 18 to 65 years
  • Diagnosed hypertension or resistant hypertension
  • STOP-Bang score ≥3 indicating high risk of obstructive sleep apnea
  • Willing and able to provide informed consent

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Kaohsiung Armed Forces General Hospital
Coordinator of this site? Confirm its status
Kaohsiung CityTaiwanRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.