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NCT07604753Recruiting

Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders

Validity of the World Health Organization CIDI 5.0 for Assessing Lifetime Prevalence of Mental Disorders: A Clinical Reappraisal Study Using the SCID-5

Source: ClinicalTrials.gov · Last updated 22 May 2026

Brief summary (registry, in English)

The World Health Organization Composite International Diagnostic Interview (CIDI) is a fully structured diagnostic tool designed for lay interviewers to assess the prevalence of mental and substance use disorders. Earlier versions, such as the CIDI 3.0, demonstrated acceptable individual-level concordance with clinical assessments based on DSM-IV criteria (Haro et al. 2006). The latest iteration (CIDI 5.0) has been updated to operationalize DSM-5 criteria. Recent evidence from a large-scale, community-based national study in Qatar suggests that under DSM-5 criteria (Khaled et al. 2024), after recalibration, the CIDI 5.0 maintains high specificity (91.9% for MDD, 94.7% for GAD, and 85.5% for PTSD). Sensitivity suggested CIDI diagnoses aligned closely with clinical "gold standard" diagnoses (51.5% for MDD, 50.7% for GAD, and 77.3% for PTSD). Despite the evidence from Qatar, there remains a lack of evidence regarding the validity of the CIDI 5.0 in population-based studies. Therefore, this study aims to evaluate the diagnostic validity of the CIDI 5.0 for Lifetime MDD, GAD, and PTSD, using the Structured Clinical Interview for DSM-5 (SCID-5) as the definitive clinical gold standard.

Status (registry)
Recruiting
Study type
Observational
Enrollment
300 (estimated)
First submitted
9 Apr 2026
Start date
14 May 2025
Primary completion date
31 Jan 2028
Lead sponsor
The University of Hong Kong
Diseases
Depression
NCT number
NCT07604753

What you commit to

  • Study type: Observational
  • Planned participants: 300
  • From 14 May 2025 to the primary completion date, 31 Jan 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Domestic workers

Who the study is looking for

  • All household members aged 18 years old and over are randomly sampled from the Census and Statistics Department List of Quarters
  • Live in the address sampled from the Census and Statistics Department List of Quarters
  • Reside in Hong Kong for at least six months in the past year
  • Able to read and communicate in Chinese or English
  • Without linguistic or cognitive difficulties

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

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SiteCityCountrySite status
The University of Hong Kong
Coordinator of this site? Confirm its status
Hong KongHong Kong SAR ChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.