NCT07604857Completed
Combined Oral and Parenteral Nutritional Therapy After Gastrectomy for Gastric Cancer
Bridging the Postoperative Nutritional Gap After Gastrectomy for Gastric Cancer: A Prospective Randomized Trial of Combined Oral and Parenteral Nutritional Therapy
Source: ClinicalTrials.gov · Last updated 22 May 2026
Brief summary (registry, in English)
Patients undergoing gastrectomy for gastric cancer frequently experience insufficient oral intake during the postoperative recovery period because of reduced gastric capacity, early satiety, and gastrointestinal symptoms. Although oral nutritional supplements (ONS) are commonly recommended, adherence is often poor, resulting in a postoperative nutritional gap. This prospective randomized clinical trial was designed to evaluate the impact of combined oral and parenteral nutritional therapy on nutritional status and recovery after gastrectomy for gastric cancer. Patients were randomized to either a combined nutritional therapy group receiving oral nutritional supplementation plus parenteral nutrition or a control group receiving standard postoperative care. The primary endpoint was postoperative body weight change at 4 weeks after surgery. Secondary endpoints included body composition, nutritional intake, inflammatory and immune markers, laboratory parameters, and quality of life outcomes.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 55 (actual)
- First submitted
- 17 May 2026
- Start date
- 1 Oct 2020
- Primary completion date
- 31 May 2024
- Lead sponsor
- Kyo Young Song
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT07604857
What you commit to
- Study type: Interventional
- Participants enrolled: 55
- From 1 Oct 2020 to the primary completion date, 31 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous chemotherapy or radiotherapy
Other illness
- Uncontrolled diabetes mellitus
- Active malignancy other than gastric cancer
- Allergy to oral nutritional supplement products
Other
- Body mass index (BMI) ≥30 kg/m² or \<18.5 kg/m²
- Severe hepatic or renal dysfunction
Who the study is looking for
- Age 20 to 80 years
- Histologically confirmed gastric cancer
- Scheduled for curative total or subtotal gastrectomy
- Ability to tolerate oral intake
- Residence within areas covered by home care services
- Written informed consent
Age in the registry: 20 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Seoul St. Mary's Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.